Isolation of Hepatitis A Virus (HAV)from Arca subcrenata Lischke in Sea
Abstract: An outbreak of hepatitis A with uncooked Arca subcrenata Lischke has been reported in shanghai in early 1988. Five specimens were collected from the sea at Qidong County Jiangsu Province vhere Produce Arca subcrenata Lischke. Specimens were made of suspension of 40% with the gill and system enteron, then treated by trichloromethane. HAY was isolated with FRHK4 cell cultrues by 21 days and passed continually two generation. All specimens are positive for HAY by IF, ELISA, HAV-cDNA dot hybridization test and ...