Citation: HUANG Tian-Min, XU Zhao-Xiang, WANG Yan-Ping, QU Feng-Zhen, TONG Ling-Li. Studies on Antiviral Activity of the Extract of Monordica Charantca and its Active Principle .VIROLOGICA SINICA, 1990, 5(4) : 367.

Studies on Antiviral Activity of the Extract of Monordica Charantca and its Active Principle

  • Available online: 05 December 1990
  • The extract of Monordica charantia (E. M. c.) was found to have a significant protective effect on Japanese B encephlitis virus infection in vivo. When mice were administered intraperitoneally with a dose of 0.4 mg E. M. c. at 18 hr, 12 hr, 4 hr before subcutaneous challenge with the virus respectively, the protective rate of treated group is 66%. E.M.c. was demonstrated as an interferon inducer. Type I IFN was found in rabbit serum and its level peaked at 2hr after intravenus injection of E. M.c. E.M.c. en...

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    Studies on Antiviral Activity of the Extract of Monordica Charantca and its Active Principle

    • 1. Institute of Virology
    • 2. Chinese Academy of Preventive Medicine

    Abstract: The extract of Monordica charantia (E. M. c.) was found to have a significant protective effect on Japanese B encephlitis virus infection in vivo. When mice were administered intraperitoneally with a dose of 0.4 mg E. M. c. at 18 hr, 12 hr, 4 hr before subcutaneous challenge with the virus respectively, the protective rate of treated group is 66%. E.M.c. was demonstrated as an interferon inducer. Type I IFN was found in rabbit serum and its level peaked at 2hr after intravenus injection of E. M.c. E.M.c. en...

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