The Viral Inclusion Bodies in the Autopsy Tissues of Patients with Epidemic Hemorrhagic Fever
Abstract: Using polyclonal antibody (PAb)and monoclonal antibodies(MAbs) against epidemic hemorrhagic fever virus (EHFV), the viral antigens in fresh and long-term storage EHF autopsy tissues were studied comparatively with more sensitive multi-layer PAP and PAP combined with ABC (PAP+ABC) techniques. The results showed that the inclusion bodies (IB) with viral antigens positive could be demonstrated in the autopsy tissues. Four types of IB, designated solid. small-bubble, big-bubble and multi-bubble, could be observ...