Citation: ZHANG Wei, JIN Shun-Qian, LIANG Xiao, SHANG Ming, SUN Jian-Heng, WANG Xi-Xia, TUN Ai-Ru. The Cloning and Characterization of the Genome of Human Papilloma Virus Type 16 in China .VIROLOGICA SINICA, 1993, 8(1) : 45.

The Cloning and Characterization of the Genome of Human Papilloma Virus Type 16 in China

  • Available online: 05 March 1993
  • The cloning and characterization of a whole genome of human Papillomavirus type 16 (7.9kb) and a 5.4kb subgenomic fragment are presented here for the first time in China. Both of them were cloned in HB101 after insertion in plasmid pAt153, using it s unique BamH1 site. The full-length genome and subgenomic fragment are designated HPV16Z and HPV16F, respectively. After analysis of 16 endonucleases, none of new endonuclease site were found in HPV16Z comparing with standard strain. A new BamH1 site was observe...

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    The Cloning and Characterization of the Genome of Human Papilloma Virus Type 16 in China

    • 1. Institute of Oncology
    • 2. CAMS

    Abstract: The cloning and characterization of a whole genome of human Papillomavirus type 16 (7.9kb) and a 5.4kb subgenomic fragment are presented here for the first time in China. Both of them were cloned in HB101 after insertion in plasmid pAt153, using it s unique BamH1 site. The full-length genome and subgenomic fragment are designated HPV16Z and HPV16F, respectively. After analysis of 16 endonucleases, none of new endonuclease site were found in HPV16Z comparing with standard strain. A new BamH1 site was observe...

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