Citation: LUO Jun, LIU Zhen-An, YANG Tie-Qiu, XIAO Gong, WEN Li. Pathogenicity of Herpes Sim plex Virus on Mice .VIROLOGICA SINICA, 1997, 12(4) : 309-312.

Pathogenicity of Herpes Sim plex Virus on Mice

  • Available online: 05 December 1997
  • The pathogenicity of herpes simplex virus(HSV)in mice宙as observed.The mice appears syndrome and sign afterinoculation 4 days HSV could beisolatedinthe blood on 2hours po$tin fection.The isolation rate of HSV and levd of viremia were increased on 48 hours postirfection. distributions of HgV wel'e differem in virious tissues.The HSV titers in brain and seusory ganglion reached the p目_k on 72 hours postinfection,but in heart and liver on 5 days.Above re sults showed that the patho geniclty model of HSV can be used to search antiHSV agents.

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    Pathogenicity of Herpes Sim plex Virus on Mice

    • 1. Guangzhou General Hospital of Chinese PLA Guangzhou 510010

    Abstract: The pathogenicity of herpes simplex virus(HSV)in mice宙as observed.The mice appears syndrome and sign afterinoculation 4 days HSV could beisolatedinthe blood on 2hours po$tin fection.The isolation rate of HSV and levd of viremia were increased on 48 hours postirfection. distributions of HgV wel'e differem in virious tissues.The HSV titers in brain and seusory ganglion reached the p目_k on 72 hours postinfection,but in heart and liver on 5 days.Above re sults showed that the patho geniclty model of HSV can be used to search antiHSV agents.

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