Establishment of a M armoset Lymphoblastoid Cell Line Releasing Transforming Epstein Barr Virus
Abstract: A lymphoblastoid cell line (KMT 3) was established by EBV induced B cell transformation in the cotton top tamarin. The viruses were prepared from the culture fluid of B 95 8 cells by passing through a 0.45μm filter. KMT 3 can produce high titer infections EB viruses. Its VCA positive cell rate was 3~5% in natural and 50~60% after activation. Human B lymphocytes could be immortalized directly from KMT 3 supernatant. The number of chromosomes was 46.