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Volume 13 Issue 2
April 1998
    Citation: LI Mao-Xiang, JIN Qi, ZHANG Jin-Gang, CENG Li-Yu, TAO Er-Mei, YAN Shen, HOU Yun-De. Cloning and Sequence Characterization of L4 Nonstructural 100K Protein Gene of Egg Drop Syndrome Virus .VIROLOGICA SINICA, 1998, 13(2) : 160.
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    Cloning and Sequence Characterization of L4 Nonstructural 100K Protein Gene of Egg Drop Syndrome Virus

    • 1.

      State Key La&aratory ofMolez-ula~r Virology and Genetic Engineering，Belting 100052The Military Veterinary Institute,University of Agricuture and Animal Science．Changchun 1319062

    • Available online: 05 June 1998
    • The nucleotide sequence and location of the L4 nonstructural 100 K protein gene of the egg drop syndrome virus (EDSV),a strain AA 2 previously isolated from China,were determined.The 100K protein gene located at 55.7-64.8 m.u.has a length of 2091 nt and codes for a polypeptide of 696 amino acids (aa)with a molecular weight of 77.7kD. Comparison of the amino acid sequence of the 100K proteins from human adenoviruses and fowl adenoviruses of group I revealed a homology from 32.3% to 34.4%.Remarkably,EDSV 100K protein shares high homology (56.4% on amino acid level)with that of ovine adenovirus.
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      Cloning and Sequence Characterization of L4 Nonstructural 100K Protein Gene of Egg Drop Syndrome Virus

      • 1. State Key La&aratory ofMolez-ula~r Virology and Genetic Engineering，Belting 100052The Military Veterinary Institute,University of Agricuture and Animal Science．Changchun 1319062

      Abstract: The nucleotide sequence and location of the L4 nonstructural 100 K protein gene of the egg drop syndrome virus (EDSV),a strain AA 2 previously isolated from China,were determined.The 100K protein gene located at 55.7-64.8 m.u.has a length of 2091 nt and codes for a polypeptide of 696 amino acids (aa)with a molecular weight of 77.7kD. Comparison of the amino acid sequence of the 100K proteins from human adenoviruses and fowl adenoviruses of group I revealed a homology from 32.3% to 34.4%.Remarkably,EDSV 100K protein shares high homology (56.4% on amino acid level)with that of ovine adenovirus.

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