Citation: ZHONG Beng, LIU Gui-Zhen, SHU Wei, DUAN Ji-Liang, ZHANG Yi-Huang. Genotyping of HIV-1 in Anti-HIV-1 Sero-Positive Plasma .VIROLOGICA SINICA, 1999, 14(1) : 17-22.

Genotyping of HIV-1 in Anti-HIV-1 Sero-Positive Plasma

  • Available online: 05 March 1999
  • Six of anti HIV 1 sero positive plasma derived from a local high risk population were investigated by RT PCR and cDNA sequencing. The results indicated that HIV 1 prevalent in a local high risk population belonged to HIV 1 subtype B. The sequences of nucleic acids and amino acids in V3 loop of 6 cDNA were completely similar to that of Thailand HIV 1 subtype B strains. Besides, the sequences of cDNA and amino acid from 6 plasma samples were identical. It implied that they might be derived from 6 HIV 1 infected people who were infected with HIV 1 at the same period. This study could provide a better understanding of prevelence of HIV 1 subtype strains in a local high risk population.

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    Genotyping of HIV-1 in Anti-HIV-1 Sero-Positive Plasma

    • 1. Shanghai Institute of Biologica[Products,Shanghai 200052

    Abstract: Six of anti HIV 1 sero positive plasma derived from a local high risk population were investigated by RT PCR and cDNA sequencing. The results indicated that HIV 1 prevalent in a local high risk population belonged to HIV 1 subtype B. The sequences of nucleic acids and amino acids in V3 loop of 6 cDNA were completely similar to that of Thailand HIV 1 subtype B strains. Besides, the sequences of cDNA and amino acid from 6 plasma samples were identical. It implied that they might be derived from 6 HIV 1 infected people who were infected with HIV 1 at the same period. This study could provide a better understanding of prevelence of HIV 1 subtype strains in a local high risk population.

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