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Volume 16 Issue 2
April 2001
    Citation: RONG Ouang-ya, ZhOU ji—wen, LEI Li, ZHAO Gui—lan, SUN Jie. Immunoreaetivity Studies of Various HEV Antigen with Anti-HEV IgM of the Sear from Patients Infected with Hepatitis E Virus .VIROLOGICA SINICA, 2001, 16(2) : 128-130.
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    Immunoreaetivity Studies of Various HEV Antigen with Anti-HEV IgM of the Sear from Patients Infected with Hepatitis E Virus

    • 1.

      Center for DiagnosticReagents，302 Hospital of LA，Belting 100039，China

    • Available online: 05 June 2001
    • Objective To compare the Iramunoreactivity of various HEV Antigen with An ti—HEV IgM Methods Solid-phase erazyrne immunoassay(EIA )vcas developed for detecting anti HEV IgM by using synthetic peptides E30，E42，E33，and recombinant antigen from HEV ORF一2 Results Of 60 anti-HEV positive sera by using E30，E42，E33 and recombina nt antigen as coating antigen，Anti— HEV IgM positive rates were 76．7％ ．26，6％ ．18 3％ and 66 7％ respectively InAcute-phase and convalescence—phase sera of the patients with Hepa titis E．An ti—HEV IgM positive rate was 90％ and 3 3％ respectively．Condusions The HEV E30一based EIA will be very useful in the early diagnosis of Hepatitis E．
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      Immunoreaetivity Studies of Various HEV Antigen with Anti-HEV IgM of the Sear from Patients Infected with Hepatitis E Virus

      • 1. Center for DiagnosticReagents，302 Hospital of LA，Belting 100039，China

      Abstract: Objective To compare the Iramunoreactivity of various HEV Antigen with An ti—HEV IgM Methods Solid-phase erazyrne immunoassay(EIA )vcas developed for detecting anti HEV IgM by using synthetic peptides E30，E42，E33，and recombinant antigen from HEV ORF一2 Results Of 60 anti-HEV positive sera by using E30，E42，E33 and recombina nt antigen as coating antigen，Anti— HEV IgM positive rates were 76．7％ ．26，6％ ．18 3％ and 66 7％ respectively InAcute-phase and convalescence—phase sera of the patients with Hepa titis E．An ti—HEV IgM positive rate was 90％ and 3 3％ respectively．Condusions The HEV E30一based EIA will be very useful in the early diagnosis of Hepatitis E．

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