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Volume 16 Issue 3
June 2001
    Citation: . Study Oil S Gene Nucleotide Sequence of Hantan SEO Type Virus in China .VIROLOGICA SINICA, 2001, 16(3) : 202-207.
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    Study Oil S Gene Nucleotide Sequence of Hantan SEO Type Virus in China

    • 1.

      1河北省保定市传染病医院，河北保定0710G0

    • 2.

      北省保定市急救巾心．河北保定071000 3巾国预防医学科学院病毒学研究所，北京10220

    • Available online: 05 September 2001
    • Epidemiologic feature of Hemorrhagic fever with renal syndrome(HFRS)is endemic outbrak by SEO type nowadays.This article is to study SEO viral genes and the cause of endemic outbreak of HFRS.Virus isolation,McAbs typing and TR-PCR were used to determine a SEO strain isolated from Hebei province in 1996.Nucleotide sequence of S gene was detected.Compared with 75-118.Seoul and SRll strains,the homologies of nucleotide sequence were 64.2%,91.8%,96.8%,respectively,amino acid sequence were 80.5%,95.4%,97.3%,repectively.The high epidemics of HFRS wasnt because of recombinant of viral genes.This study provides important material for the cause of HFRS outbreak.
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      Study Oil S Gene Nucleotide Sequence of Hantan SEO Type Virus in China

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      • 1. 1河北省保定市传染病医院，河北保定0710G0
      • 2. 北省保定市急救巾心．河北保定071000 3巾国预防医学科学院病毒学研究所，北京10220

      Abstract: Epidemiologic feature of Hemorrhagic fever with renal syndrome(HFRS)is endemic outbrak by SEO type nowadays.This article is to study SEO viral genes and the cause of endemic outbreak of HFRS.Virus isolation,McAbs typing and TR-PCR were used to determine a SEO strain isolated from Hebei province in 1996.Nucleotide sequence of S gene was detected.Compared with 75-118.Seoul and SRll strains,the homologies of nucleotide sequence were 64.2%,91.8%,96.8%,respectively,amino acid sequence were 80.5%,95.4%,97.3%,repectively.The high epidemics of HFRS wasnt because of recombinant of viral genes.This study provides important material for the cause of HFRS outbreak.

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