Genotyping of Hepatitis C Virus in Hebei Province
Abstract: Abstract:Using nested RT—PCR an d type special primers of HCV,we performed genotype an alysis of HCV RNA from five representative cities in Hebei Province.Among 168 samples with HCV RNA,104 sera was typelb(61.9%),type 2a account for 22.6% (38/168),and lb/2a mixed—type was 15.5% (26/168).The results indicate that typelb is the dominance strain in Hebei Province.Compared with type 2a,type lb has important relationship with chronic hepatitis C.This study build 叩some foundations for diagnosis,treatment and vaccine study of hepatitis C.