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Volume 19 Issue 5
October 2004
    Citation: YIN Hong-yan, DENG Gang, SHA Ri-na, QIAO Wen-tao, GENG Yun-qi, CHEN Qi-min*. Primary Study on the Interaction of JDV and Other Three Bovine Retroviruses .VIROLOGICA SINICA, 2004, 19(5) : 471-475.
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    Primary Study on the Interaction of JDV and Other Three Bovine Retroviruses

    • 1.

      College of Life Science, Nankai University, Tianjin 300071, China

    • Available online: 20 October 2004
    • To study the interaction among Jembrana disease virus, Bovine immunodeficiency virus, Bovine Foamy Virus and Bovine Leukemia Virus, a series of plasmids were constructed with their LTR and luc report gene, respectively, and transactivator expression plasmids of these four viruses were also constructed. These plasmids were co-transfected into BL12 cell line, respectively. Transient assay showed the interactivation between LTR and Tat of BIV and JDV, suggesting that they could be transactivated each other. In addition, BFV Tas could transactivate JDV LTR and JDV Tat could transactivate BLV LTR whereas BLV Tax had no effect on JDV LTR and no other interactivation was detected among BLV, BFV and BIV.
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      Primary Study on the Interaction of JDV and Other Three Bovine Retroviruses

      • 1. College of Life Science, Nankai University, Tianjin 300071, China

      Abstract: To study the interaction among Jembrana disease virus, Bovine immunodeficiency virus, Bovine Foamy Virus and Bovine Leukemia Virus, a series of plasmids were constructed with their LTR and luc report gene, respectively, and transactivator expression plasmids of these four viruses were also constructed. These plasmids were co-transfected into BL12 cell line, respectively. Transient assay showed the interactivation between LTR and Tat of BIV and JDV, suggesting that they could be transactivated each other. In addition, BFV Tas could transactivate JDV LTR and JDV Tat could transactivate BLV LTR whereas BLV Tax had no effect on JDV LTR and no other interactivation was detected among BLV, BFV and BIV.

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