Serving the Society Since 1986
Advanced Search
Volume 21 Issue 4
August 2006
    Citation: LI Mei-rong, TANG Tai-shan, ZHANG Chang-yin, WANG Kai-min, LI Ming-jie, CHEN Jia-qiu, LU Cheng-ping. Immuuological Surey of Canine Distemper in Large Felids in Zoos .VIROLOGICA SINICA, 2006, 21(4) : 368-370.
    shu

    Immuuological Surey of Canine Distemper in Large Felids in Zoos

    • 1.

      1.Nanjing Forest Zoo, Nanjing 210028, China

    • 2.

      Jiangsu Entry-Exit Inspection and Quarantine Bureau, Nanjing 210001, China

    • 3.

      Key Lab of Animal Disaese Diagnostic & Immunology, Ministry of Agriculture, Nanjing Agricultural University, Nanjing 210095, China

    • Corresponding author: LU Cheng-ping, 
    • Available online: 20 July 2006
    • Large felids, such as tigers, lions and leopards are often infected with Canine Distemper (CD). Blood samples from pre-immune Amur tiger, African lion and lynx were collected and the antibody against CDV was measured by neutralization tests. The results showed that their CDV antibody level were all below 1:5. After inoculated with attenuated CD vaccine, the young animals produced antibody in 14 days but the antibody levels of the adults increased rapidly within two months and maintained at titer of 1: 64, then gradually dropped after 9 to 11 months. After booster immunizing, antibody level went up rapidly to≥1:112. The vaccination was safe to the animals. Achroia Indian tiger, however, could not produce CDV neutralizing antibody after vaccination.
    • 加载中
    • 加载中
    PDF

    Article Metrics

    Article views(4734) PDF downloads(1005) Cited by()

    Related
    Proportional views

      Immuuological Surey of Canine Distemper in Large Felids in Zoos

        Corresponding author: LU Cheng-ping,
      • 1. 1.Nanjing Forest Zoo, Nanjing 210028, China
      • 2. Jiangsu Entry-Exit Inspection and Quarantine Bureau, Nanjing 210001, China
      • 3. Key Lab of Animal Disaese Diagnostic & Immunology, Ministry of Agriculture, Nanjing Agricultural University, Nanjing 210095, China

      Abstract: Large felids, such as tigers, lions and leopards are often infected with Canine Distemper (CD). Blood samples from pre-immune Amur tiger, African lion and lynx were collected and the antibody against CDV was measured by neutralization tests. The results showed that their CDV antibody level were all below 1:5. After inoculated with attenuated CD vaccine, the young animals produced antibody in 14 days but the antibody levels of the adults increased rapidly within two months and maintained at titer of 1: 64, then gradually dropped after 9 to 11 months. After booster immunizing, antibody level went up rapidly to≥1:112. The vaccination was safe to the animals. Achroia Indian tiger, however, could not produce CDV neutralizing antibody after vaccination.

        HTML

      Relative (20)

      目录

      This journal is a member of, and subscribes to the principles of, the Committee on Publication Ethics (COPE)

      鄂ICP备05001977号

         

      鄂公网安备 42010602003674号

      Copyright © 2019 Virologica Sinica. All rights reserved

      /

      DownLoad:  Full-Size Img  PowerPoint
      Return
      Return