Study of HBV like Hepatitis Virus in the Marmota sibirica

BAI Feng; LI Chun-Ying; ZHAO Ri-Ge-Tai; WU Bing-Ren; JING He; DONG Jie

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February 1989

BAI Feng, LI Chun-Ying, ZHAO Ri-Ge-Tai, WU Bing-Ren, JING He and DONG Jie. Study of HBV like Hepatitis Virus in the Marmota sibirica[J]. Virologica Sinica, 1989, 4(1).

Citation: BAI Feng, LI Chun-Ying, ZHAO Ri-Ge-Tai, WU Bing-Ren, JING He, DONG Jie. Study of HBV like Hepatitis Virus in the Marmota sibirica .VIROLOGICA SINICA, 1989, 4(1) : 85.

西伯利亚旱獭中类人乙肝病毒的研究

1.
内蒙古卫生防疫站
2.
内蒙古卫生防疫站呼和浩特
3.
呼和浩特

摘要

对111份西伯利亚旱獭血清标本进行血清学,形态和组织病理学检测,HBsAg阳性22份,阳性率19.8％;抗-HBs1份,阳性率0.9％;HBV-DNA核酸杂交,阳性斑点16份,阳性率14.4％。IEM观察在3份标本中发现以22—24nm球形颗粒为主,其中有42—45mm的Dane样颗粒。20.7％的肝脏标本有组织病理改变,其中19份为急性肝类,4份为慢性肝炎。超薄切片肝细胞核内有20nm左右的HBeAg颗粒,结果进一步证实我国西伯利亚旱獭中有嗜肝病毒感染。
- 旱獭
- , 嗜肝病毒
- , 肝炎

Study of HBV like Hepatitis Virus in the Marmota sibirica

1.
Nci Mongolia Anti-Epidemic Station
2.
Huhehote

Abstract

Blood samples and liver biopsy sections of 111 Marmota sibirica were studied for WHV infection. The scrum samples were assayed for HBV surface antigen, anti-HBs and HBV-DNA. Some of them were observed morphologically by IEM. 22 of 111 scra were positive for HBV surface antigen(19.8%), one positive for anti-HBs(0.9%) and 31 positive for HBV-DNA detected by spot hybridization method. Typical round HBV-like particles were seen. Most of them were 22-24nm in diameter,only a few were 42-45 nm in diameter.Dane par...
- Marmota sibirica
- , Hepadna Virus
- , Hepatitis

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Study of HBV like Hepatitis Virus in the Marmota sibirica

1. Nci Mongolia Anti-Epidemic Station
2. Huhehote

Abstract: Blood samples and liver biopsy sections of 111 Marmota sibirica were studied for WHV infection. The scrum samples were assayed for HBV surface antigen, anti-HBs and HBV-DNA. Some of them were observed morphologically by IEM. 22 of 111 scra were positive for HBV surface antigen(19.8%), one positive for anti-HBs(0.9%) and 31 positive for HBV-DNA detected by spot hybridization method. Typical round HBV-like particles were seen. Most of them were 22-24nm in diameter,only a few were 42-45 nm in diameter.Dane par...