Significance of Koilocyte in the Diagnosis of Human Papillomavirus Infection of Cervix

MENG Xiang-Jin; SUN Yu; ZHANG Wei-Xin; LI Xin-Zhi; LIU Zhi-Hui; CHEN Min-Hui; LI Hun; HAN Ri-Cai; SI Jing-Yi; CENG Wei-Kun; HU Lun-Ying

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April 1989

MENG Xiang-Jin, SUN Yu, ZHANG Wei-Xin, LI Xin-Zhi, LIU Zhi-Hui, CHEN Min-Hui, LI Hun, HAN Ri-Cai, SI Jing-Yi, CENG Wei-Kun and HU Lun-Ying. Significance of Koilocyte in the Diagnosis of Human Papillomavirus Infection of Cervix[J]. Virologica Sinica, 1989, 4(2).

Citation: MENG Xiang-Jin, SUN Yu, ZHANG Wei-Xin, LI Xin-Zhi, LIU Zhi-Hui, CHEN Min-Hui, LI Hun, HAN Ri-Cai, SI Jing-Yi, CENG Wei-Kun, HU Lun-Ying. Significance of Koilocyte in the Diagnosis of Human Papillomavirus Infection of Cervix .VIROLOGICA SINICA, 1989, 4(2) : 146.

空泡细胞在诊断宫颈人乳头瘤病毒感染中的意义

1.
湖北医学院病毒研究所
2.
中国医学科学院基础所
3.
湖北医学院附属二院妇产科
4.
湖北医学院附属二院妇产科山东医学科学院基础医学研究所

摘要

本文对空泡细胞(Koilocyte)的形态进行了光镜和电镜观察,并应用分子杂交技术和PAP染色的方法对宫颈疾患中人乳头瘤病毒(HPV)DNA和抗原进行了检测,分析HPV DNA及抗原检测结果与空泡细胞出现的关系发现,空泡细胞阳性的病例中HPV DNA及抗原的检出率较低,并且部分空泡细胞阳性的病例中也可测出疱疹病毒Ⅱ型(HSV_2)抗原,结果提示:空泡细胞并不是HPV感染所特有的,空泡细胞作为诊断宫颈HPV感染的特征性指标值得怀疑。
- 空泡细胞
- , 人乳头瘤病毒
- , 疱疹病毒Ⅱ型
- , 分子杂交
- , PAP染色

Significance of Koilocyte in the Diagnosis of Human Papillomavirus Infection of Cervix

1.
Virus Research Institute
2.
Hubei Medical College
3.
WuhanInstitute of basic Medical Science
4.
Chinese Academy of Medical Science

Abstract

The morphology of koilocyte was observed by light and electronic microscopes, a series of clinical cervical lesions were studied in the presence of human papilloma virus (HPV)DNA and antigens by molecular hybridization and PAP staining method. Having analysed the correlation of the detection of HPV DNA and antigens with the occurence of koilocyte, we found that the detection of HPV DNA and antigens was relative lower in the positive cases of koilocyte, and some lesions with koilocyte can also be used to det...
- Koilocyte
- , Human papillomavirus
- , Herpes simplex virus-2
- , PAP staining
- , Molecular hybridization

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Significance of Koilocyte in the Diagnosis of Human Papillomavirus Infection of Cervix

1. Virus Research Institute
2. Hubei Medical College
3. WuhanInstitute of basic Medical Science
4. Chinese Academy of Medical Science

Abstract: The morphology of koilocyte was observed by light and electronic microscopes, a series of clinical cervical lesions were studied in the presence of human papilloma virus (HPV)DNA and antigens by molecular hybridization and PAP staining method. Having analysed the correlation of the detection of HPV DNA and antigens with the occurence of koilocyte, we found that the detection of HPV DNA and antigens was relative lower in the positive cases of koilocyte, and some lesions with koilocyte can also be used to det...