TANG Hua and REN Zhong-Yuan. The Studied Advances of Structure and in Vitro Expression of the Hepatitis B Virus Genome[J]. Virologica Sinica, 1990, 5(1).
Citation:
TANG Hua, REN Zhong-Yuan.
The Studied Advances of Structure and in Vitro Expression of the Hepatitis B Virus Genome .VIROLOGICA SINICA, 1990, 5(1)
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摘要
人乙型肝炎病毒(HBV)不仅能引起人类急慢性肝炎,而且还可导致原发性肝癌的形成。然而,遗憾的是至今尚无有效的办法来防治HBV的感染。近年来,由于基因重组技术的发展,加速了HBV的研究进程,HBV的基因结构,转录及增殖特性已基本弄清,并且整合在原发性肝癌细胞染色体上的HBV DNA序列亦被证实。同时采用多种载体系统重组HBV DNA片段,在体外已成功地表达了乙型肝炎表面抗原(HBsAg),
The Studied Advances of Structure and in Vitro Expression of the Hepatitis B Virus Genome