XIONG Kai-Jun, Wang-Xin-He, Huang-Hua-Fang, Ceng-Lian-Lan, Yang-Ze-Chuan, Ling-Mei-Xia and Zhang-Xue-Zhen. Follow-up Observation on Antiviral Effect of Acyclovir in Chronic Hepatitis B Virus Infection[J]. Virologica Sinica, 1990, 5(2).
Citation:
XIONG Kai-Jun, Wang-Xin-He, Huang-Hua-Fang, Ceng-Lian-Lan, Yang-Ze-Chuan, Ling-Mei-Xia, Zhang-Xue-Zhen.
Follow-up Observation on Antiviral Effect of Acyclovir in Chronic Hepatitis B Virus Infection .VIROLOGICA SINICA, 1990, 5(2)
: 130.
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摘要
慢性乙型肝炎病毒感染s5例,随机分无环鸟苷长程组22例,短程组11例和对照组22例。经一年随访观察,无环鸟苷治疗组见血清HBeAg、DNA-P和HBV-DNA有规律性阴转,短程组于12个月又有部分指标阳转,长程组阴转较多,其血清HBeAg、DNA-P和HBV-DNA阴转率与短程和对照组比较有显著性差异。一年结果四项病毒复制指标全部阴转例数与对照组有显著性差异,结果表明,无环鸟苷长疗程是有较好疗效。
Follow-up Observation on Antiviral Effect of Acyclovir in Chronic Hepatitis B Virus Infection
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Abstract
55 patients with chronic infection of hepatitis B virus were divided into three groups: the long time treatment group(LTTG) were 22 cases, the short time treatment group(STTG) were 11 cases and the control group were 22 cases.All patients have been follow-up for one year,the serum HBeAG, DNAP and HBV-DNA turned into negative regularly in the groups treated with acyclovir at 3-6 months after treatment,but a part of viral replicative markers turned into positive again at 12 months in the STTG, the negative ra...
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References
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Proportional views
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