Molecular Epidemic Study for Adenovirus type 3 and 7 Causing Children Pneumonia in the Areas of Changchun

FU Wen-Yong; LIANG Dong; Zheng Yong-Chen; LIU Wei-Min; XU Zhong; GUO Hui-Jun; YUAN Tong-Fu

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April 1990

FU Wen-Yong, LIANG Dong, Zheng Yong-Chen, LIU Wei-Min, XU Zhong, GUO Hui-Jun and YUAN Tong-Fu. Molecular Epidemic Study for Adenovirus type 3 and 7 Causing Children Pneumonia in the Areas of Changchun[J]. Virologica Sinica, 1990, 5(2).

Citation: FU Wen-Yong, LIANG Dong, Zheng Yong-Chen, LIU Wei-Min, XU Zhong, GUO Hui-Jun, YUAN Tong-Fu. Molecular Epidemic Study for Adenovirus type 3 and 7 Causing Children Pneumonia in the Areas of Changchun .VIROLOGICA SINICA, 1990, 5(2) : 142.

长春地区引起婴幼儿肺炎的3、7型腺病毒分子流行病学研究

1.
白求恩医科大学第一临床医院儿科
2.
长春市凯旋药厂研究所长春

摘要

本文对长春地区1976年—1988年引起小儿肺炎的135株3.7型腺病毒核酸进行了限制性内切酶图谱分析,结果表明:75株7型腺病毒经BamHⅠ、BelⅠ、BglⅠ、XbaⅠ、SmaⅠ、HindⅢ分析后表现为二个基因组型—7b和7d。其中60株7b(88％),流行于1976—1988年;15株7d(12％)自1982年出现逐年增加,到1987—1988年的5株都是7d。60株3型腺病毒被BglⅡ、BamHⅠ分析后表现为三个基因组型,我们用3Ⅰ、3Ⅱ、3Ⅲ代表它们,其中S6株3Ⅰ(93.3％)流行于1976—1888年;3Ⅱ、3Ⅲ散在分布。通过临床资料整理,发现该地区3.7型腺病毒的不同基因组型在毒力致病性上存在着差别。
- 腺病毒
- , 基因组型
- , 限制性内切酶
- , 分子流行病学

Molecular Epidemic Study for Adenovirus type 3 and 7 Causing Children Pneumonia in the Areas of Changchun

1.
The First Theathing Hospital
2.
Bethune University of the Medical Science

Abstract

This paper reports the DNA restriction endonuclease analysis of 102 strains adenovirus 3(Ad3) and 7(Ad) causing infant pneumonia from 1976 to 1986 in the areas of Changchun. The results showed that 2 genomes of 56 strains Ad7,7b and 7d were identified by using restriction endonuclease BamHl, Bcll, XbaI, SmaI and HindⅢ. Among them 60 strains were 7b and 15 were 7d which occurred from 1982 and tended to increase with time. 3 genomes of 60 strains Ad3 were identified by using BamHI and BgIⅡ, we named them by 3...
- Adenovirus
- , Genome
- , Molecular epidemi ogy
- , Restriction endonuclease

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Molecular Epidemic Study for Adenovirus type 3 and 7 Causing Children Pneumonia in the Areas of Changchun

1. The First Theathing Hospital
2. Bethune University of the Medical Science

Abstract: This paper reports the DNA restriction endonuclease analysis of 102 strains adenovirus 3(Ad3) and 7(Ad) causing infant pneumonia from 1976 to 1986 in the areas of Changchun. The results showed that 2 genomes of 56 strains Ad7,7b and 7d were identified by using restriction endonuclease BamHl, Bcll, XbaI, SmaI and HindⅢ. Among them 60 strains were 7b and 15 were 7d which occurred from 1982 and tended to increase with time. 3 genomes of 60 strains Ad3 were identified by using BamHI and BgIⅡ, we named them by 3...