The Adaptation of Rabies Virus, Strains in Vero Cell

ZENG Rong-Fang; Chen A-Gen; ZHANG Ying; HUANG Hai-Wu

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June 1990

ZENG Rong-Fang, Chen A-Gen, ZHANG Ying and HUANG Hai-Wu. The Adaptation of Rabies Virus, Strains in Vero Cell[J]. Virologica Sinica, 1990, 5(3).

Citation: ZENG Rong-Fang, Chen A-Gen, ZHANG Ying, HUANG Hai-Wu. The Adaptation of Rabies Virus, Strains in Vero Cell .VIROLOGICA SINICA, 1990, 5(3) : 285.

狂犬病固定毒Vero细胞适应株的建立

1.
卫生部上海生物制品研究所病毒研究室
2.
卫生部上海生物制品研究所病毒研究室上海

摘要

本文报道狂犬病毒Vero细胞适应株建株经过以及对适应株的抗原和免疫原性分析的情况,并推荐“RFD”和“Hs_3”适应株作为狂犬疫苗微载体培养系统的候选毒株。
- 狂犬固定毒
- , Vero细胞
- , 适应传代

The Adaptation of Rabies Virus, Strains in Vero Cell

1.
Research Laboratory of Virology
2.
Shanghai Institute of Biological Products

Abstract

Rabies is one of the serious infective diseases in China. More than 5 million people per year are wounded by animals. The yield of hamster kidney rabies vaccine produced in China every year is not enough to meet the practical need. So we attempt to develop a Veto cell rabies vaccine with microcarrier system for large scale production. In this paper, the aG virus strain, a Chinese rabies fixed virus used for preparing primary hamster kidney cell vaccine in China since 1980, was adapted in Vero cell. 2 adap...
- Rabies fixed virus Vero cell line Adaptive passage

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

The Adaptation of Rabies Virus, Strains in Vero Cell

1. Research Laboratory of Virology
2. Shanghai Institute of Biological Products

Abstract: Rabies is one of the serious infective diseases in China. More than 5 million people per year are wounded by animals. The yield of hamster kidney rabies vaccine produced in China every year is not enough to meet the practical need. So we attempt to develop a Veto cell rabies vaccine with microcarrier system for large scale production. In this paper, the aG virus strain, a Chinese rabies fixed virus used for preparing primary hamster kidney cell vaccine in China since 1980, was adapted in Vero cell. 2 adap...