Efficacy of Treating Chronic Hepatitis B with HB Vaccine and Small Doses of Interferon and Thymosin

AO Wen-Ban; HUANG Pu-Chang; WANG Xing-Bo; Tun-Tao-Lin; ZHOU Ke-Cha; ZHANG Xiu-Hui; ZHANG Yuan-Yang; LIN Ke-Yong

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August 1990

AO Wen-Ban, HUANG Pu-Chang, WANG Xing-Bo, Tun-Tao-Lin, ZHOU Ke-Cha, ZHANG Xiu-Hui, ZHANG Yuan-Yang and LIN Ke-Yong. Efficacy of Treating Chronic Hepatitis B with HB Vaccine and Small Doses of Interferon and Thymosin[J]. Virologica Sinica, 1990, 5(4).

Citation: AO Wen-Ban, HUANG Pu-Chang, WANG Xing-Bo, Tun-Tao-Lin, ZHOU Ke-Cha, ZHANG Xiu-Hui, ZHANG Yuan-Yang, LIN Ke-Yong. Efficacy of Treating Chronic Hepatitis B with HB Vaccine and Small Doses of Interferon and Thymosin .VIROLOGICA SINICA, 1990, 5(4) : 379.

乙肝疫苗与小剂量干扰素、胸腺素联合应用对慢性乙肝抗病毒治疗效果的研究

1.
江苏省连云港市卫生防疫站
2.
江苏省连云港市罐头食品厂连云港
3.
连云港

摘要

本文用乙肝疫苗与小剂量干扰素等药物配伍治疗慢性乙肝及慢性病毒携带者。经一个疗程后,干扰素组、胎盘肽组和乙肝疫苗组HBsAg转阴率分别为13.7％,5.9％和0％;HBeAg转换率分别为68.8％,72.7％和20％。表明干扰素和免疫增强剂配伍对乙肝病毒复制有一定抑制作用,促使HBeAg转换,但对清除HBsAg无效。
- 乙肝疫苗
- , α-干扰素
- , 胸腺素
- , 胎盘肽
- , 乙肝病毒

Efficacy of Treating Chronic Hepatitis B with HB Vaccine and Small Doses of Interferon and Thymosin

1.
Lianyungang Health and Anti-epidemic Station
2.
Lianyungang 222003Lianyungang Canned Food Factory
3.
Lianyungang 222003

Abstract

In this paper chronic hepatitis B and its virus carriers were treated with HB Vaccine and small doses of interferon and thymosin. After one course of interferon group, placenta peptide group and HB-Vaccine group, the negative percentage of HBsAg were 13.7%, 5.9% and 0%, respectively. The changes of HBeAg were 68.8%, 72.7% and 20%, respectively. The results showed that combination of interferon and immunologic stimulant can control the replication of Hepatitis B Virus, and impel HBeAg to change, but can not ...
- HB-Vaccine
- , α-interferon
- , Thymosin
- , Placenta peptide
- , Hepatitis B

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Efficacy of Treating Chronic Hepatitis B with HB Vaccine and Small Doses of Interferon and Thymosin

1. Lianyungang Health and Anti-epidemic Station
2. Lianyungang 222003Lianyungang Canned Food Factory
3. Lianyungang 222003

Abstract: In this paper chronic hepatitis B and its virus carriers were treated with HB Vaccine and small doses of interferon and thymosin. After one course of interferon group, placenta peptide group and HB-Vaccine group, the negative percentage of HBsAg were 13.7%, 5.9% and 0%, respectively. The changes of HBeAg were 68.8%, 72.7% and 20%, respectively. The results showed that combination of interferon and immunologic stimulant can control the replication of Hepatitis B Virus, and impel HBeAg to change, but can not ...