Finding of Fusion Cells from the EHF Patients Urine and Its Significance

MA Li-Xian; NI Da-Shi; DONG Chao-Yang; WANG Ling-Shu

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April 1991

MA Li-Xian, NI Da-Shi, DONG Chao-Yang and WANG Ling-Shu. Finding of Fusion Cells from the EHF Patients Urine and Its Significance[J]. Virologica Sinica, 1991, 6(2).

Citation: MA Li-Xian, NI Da-Shi, DONG Chao-Yang, WANG Ling-Shu. Finding of Fusion Cells from the EHF Patients Urine and Its Significance .VIROLOGICA SINICA, 1991, 6(2) : 117.

流行性出血热患者尿液中融合细胞的检测及其意义

1.
山东医科大学预防医学系
2.
山东医科大学预防医学系济南 250012 安徽省医学科学研究所病毒室合肥
3.
济南 250012 安徽省医学科学研究所病毒室合肥

摘要

我们观察到流行性出血热患者尿液中的“多核巨细胞”并非是上皮细胞脱落后的偶然堆积,而是细胞之间发生了融合。经免疫组化染色发现所有融合细胞内均有特异性EHF病毒抗原颗粒。提示流行性出血热病毒的直接作用与尿液中融合细胞的形成有关。
- 流行性出血热
- , 融合细胞
- , 尿液
- , 病毒抗原
- , 免疫组化

Finding of Fusion Cells from the EHF Patients Urine and Its Significance

1.
Dept. of Preventive Medicine
2.
Shandong Medical University
3.
Jinan 250012

Abstract

We observed that so called mutinucleated giant cells in the EHF patients urine were not occasionally accumulated but fused by epthelial cells. We found that EHF virus antigen which were detected by immunoperoxidase technique in all the fusion cells The results indicated that the fusion cells should be closely related to EHF virus.
- Epidemic hemorrhagic fever Viral antigen Urine Fusion cells Immunoperoxidase technique

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Finding of Fusion Cells from the EHF Patients Urine and Its Significance

1. Dept. of Preventive Medicine
2. Shandong Medical University
3. Jinan 250012

Abstract: We observed that so called mutinucleated giant cells in the EHF patients urine were not occasionally accumulated but fused by epthelial cells. We found that EHF virus antigen which were detected by immunoperoxidase technique in all the fusion cells The results indicated that the fusion cells should be closely related to EHF virus.