Preliminary Studies on Cellular Receptor for Dengue-2 Virus

HONG Ding-Yan; GUO Hui-Yu

PDF
Cite
Share

facebook

twitter

google

linkedin

June 1991

HONG Ding-Yan and GUO Hui-Yu. Preliminary Studies on Cellular Receptor for Dengue-2 Virus[J]. Virologica Sinica, 1991, 6(3).

Citation: HONG Ding-Yan, GUO Hui-Yu. Preliminary Studies on Cellular Receptor for Dengue-2 Virus .VIROLOGICA SINICA, 1991, 6(3) : 187.

登革热Ⅱ型病毒受体的初步研究

汪玎妍 ,
郭辉玉

1.
广东省老年医学研究所病毒室
2.
广州市中山二路中山医科大学微生物学与免疫学教研室广州

摘要

本实验用甲基纤维素复盖层的c_6/36单层细胞微量蚀斑法的间接免疫荧光法,初步观察了登革热Ⅱ型病毒与靶细胞的联接反应情况。同时还制备了四种细胞的可溶性膜制剂,并研究了它们对登革热Ⅱ型病毒的抑制活性。结果提示,对登革热Ⅱ型病毒敏感的细胞表面存在登革热Ⅱ型病毒受体,在触发病毒感染阶段起重要作用。
- 登革热Ⅱ型病毒
- , 联接反应分析
- , 可溶性膜制剂
- , 病毒受体

Preliminary Studies on Cellular Receptor for Dengue-2 Virus

1.
Department of Microbiology
2.
Sun Yatsen University Medical Sciences

Abstract

To investigate the role of viral receptor in the initiation of dengue virus infection, viral attachment rates (AR) on Aedes albopictus cell (C6/36), human monocyte-like cell (U937), human T4 (H9),B lymphoblastoid cell(Raji), mouse myeloma cell (SP2/0) and mouse fibroblast cell (L929) were calculated by measuring the residual virus concentration after inoculating a known dose of Den-2 virus upon the above 6 cell lines and then keeping the cells at 4℃ for 15, 30 and 90 mino.The results showed that the ARs of ...
- Dengue-2 virus Attachment assay Solubilized cellular membrane （SCM） Virus receptor

References
Proportional views

PDF

Article Metrics

Article views(3637) PDF downloads(817) Cited by(0)

Proportional views

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Preliminary Studies on Cellular Receptor for Dengue-2 Virus

1. Department of Microbiology
2. Sun Yatsen University Medical Sciences

Abstract: To investigate the role of viral receptor in the initiation of dengue virus infection, viral attachment rates (AR) on Aedes albopictus cell (C6/36), human monocyte-like cell (U937), human T4 (H9),B lymphoblastoid cell(Raji), mouse myeloma cell (SP2/0) and mouse fibroblast cell (L929) were calculated by measuring the residual virus concentration after inoculating a known dose of Den-2 virus upon the above 6 cell lines and then keeping the cells at 4℃ for 15, 30 and 90 mino.The results showed that the ARs of ...