Comparison of the Immunogenicity of Three Grass Carp Hemorrhage Viruses

KE Li-Hua; TU Lan-Fen; FANG Qin; DING Qing-Quan; CAI Yi-Quan

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June 1991

KE Li-Hua, TU Lan-Fen, FANG Qin, DING Qing-Quan and CAI Yi-Quan. Comparison of the Immunogenicity of Three Grass Carp Hemorrhage Viruses[J]. Virologica Sinica, 1991, 6(3).

Citation: KE Li-Hua, TU Lan-Fen, FANG Qin, DING Qing-Quan, CAI Yi-Quan. Comparison of the Immunogenicity of Three Grass Carp Hemorrhage Viruses .VIROLOGICA SINICA, 1991, 6(3) : 248.

三株草鱼出血病病毒免疫原性的比较

1.
中国科学院武汉病毒研究所
2.
中国科学院武汉病毒研究所武汉

摘要

从湖南邵阳、湖北仙桃、武汉南湖地区分离到的三株草鱼出血病病毒(GCHV873、GCHV875、GCHV876),分别对家兔进行免疫,并测定了它们在家兔体内形成抗体的水平以及这些抗体对相应抗原的中和能力。实验结果显示:GCHV873产生抗体滴度比GCHV875高一倍,较GCHV876高8倍;其抗体的中和效价分别是1:1778(10~(-3.25))、1:386(10~-(2.59))和1:181(10~-(2.25))。上述结果表明:GCHV873的免疫原性是三个分离株中最强的一个毒株。
- 草鱼出血病病毒
- , 免疫原性
- , 抗体滴价
- , 中和试验

Comparison of the Immunogenicity of Three Grass Carp Hemorrhage Viruses

1.
Wuhan Institute of Virology
2.
Academia Sinica

Abstract

The immunogenic comparison of three grass carp hemorrhage viruses, GCHV873, GCHV875 and GCHV876 derived from different areas has been carried out on the basis of the levels of the elicited serum antibodies in rabbits. The anti-GCHV873 antibody titre was 2 folds higher than GCHV875 and 8 folds than GCHV876. Their neutralizing titres were 1 : 1778(10~(-3.25)), 1: 386(10~(-2.59)) and 1: 181(10~(-2.25)) respectively.These experimental results suggested that GCHV873 is a stronger immunogen among three isolates.
- Grass Carp Hemorrhage Virus Immunogenicity Antibody titre Neutralizing test

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Comparison of the Immunogenicity of Three Grass Carp Hemorrhage Viruses

1. Wuhan Institute of Virology
2. Academia Sinica

Abstract: The immunogenic comparison of three grass carp hemorrhage viruses, GCHV873, GCHV875 and GCHV876 derived from different areas has been carried out on the basis of the levels of the elicited serum antibodies in rabbits. The anti-GCHV873 antibody titre was 2 folds higher than GCHV875 and 8 folds than GCHV876. Their neutralizing titres were 1 : 1778(10~(-3.25)), 1: 386(10~(-2.59)) and 1: 181(10~(-2.25)) respectively.These experimental results suggested that GCHV873 is a stronger immunogen among three isolates.