Detection of Human Papillomavirus DNA from Epithelial Lessions of Vulvar Dystrophies by lsotope-labelled DNA Probes

ZHANG Li-Ning; ZHOU Li-Hua; GAI Qi-Wei; LIU Xiao-Ming; GAO Tian-Xiang

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August 1991

ZHANG Li-Ning, ZHOU Li-Hua, GAI Qi-Wei, LIU Xiao-Ming and GAO Tian-Xiang. Detection of Human Papillomavirus DNA from Epithelial Lessions of Vulvar Dystrophies by lsotope-labelled DNA Probes[J]. Virologica Sinica, 1991, 6(4).

Citation: ZHANG Li-Ning, ZHOU Li-Hua, GAI Qi-Wei, LIU Xiao-Ming, GAO Tian-Xiang. Detection of Human Papillomavirus DNA from Epithelial Lessions of Vulvar Dystrophies by lsotope-labelled DNA Probes .VIROLOGICA SINICA, 1991, 6(4) : 304.

外阴皮肤营养不良组织中人乳头瘤病毒DNA的检测

1.
山东医科大学电镜室
2.
首都医学院电镜室
3.
首都医学院电镜室济南

摘要

采用Southern Blot分子杂交方法检测了9例外阴皮肤营养不良组织中人乳头瘤病毒DNA的存在情况。结果显示8例增生型营养不良组织中,2例HPV-16阳性,1例HPV33阳性,在3例组织中探测到HPV16相关序列,在1例混合型中也检测到HPV16相关序例,HPV DNA的总检出率为77％。结果提示外阴皮肤营养不良的发生可能与HPV感染有关。
- 核酸分子杂交
- , 人乳头瘤病毒
- , 外阴皮肤营养不良症

Detection of Human Papillomavirus DNA from Epithelial Lessions of Vulvar Dystrophies by lsotope-labelled DNA Probes

1.
Laboratory of Electron Microscopy
2.
Shandong Medical University
3.
Jinan 250012

Abstract

Vulvar biopsy specimens from nine patients with vulvar dystrophy were examined for the presence of human papillomavirus DNA by Southern blot hybridization. The results showed that two of eight hypcrplastic dystrophies contained HPV 16 homologous sequence, one contained HPV 33 homologous sequence and three cases were positive for HPV relative sequence HPV relative sequence was also detected in one case with mixed dystrophy. So total proportion of HPV in the nine vulvar specimens was seventy seven percent, Th...
- Molecular Hybridization of Nucleic Acid Human Papillomvirus Vulvar dystrophy

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Detection of Human Papillomavirus DNA from Epithelial Lessions of Vulvar Dystrophies by lsotope-labelled DNA Probes

1. Laboratory of Electron Microscopy
2. Shandong Medical University
3. Jinan 250012

Abstract: Vulvar biopsy specimens from nine patients with vulvar dystrophy were examined for the presence of human papillomavirus DNA by Southern blot hybridization. The results showed that two of eight hypcrplastic dystrophies contained HPV 16 homologous sequence, one contained HPV 33 homologous sequence and three cases were positive for HPV relative sequence HPV relative sequence was also detected in one case with mixed dystrophy. So total proportion of HPV in the nine vulvar specimens was seventy seven percent, Th...