HUANG Wen-Li, ZI Deng-Yun and HOU Zong-Liu. Study on the Susceptibility of Animal to Yunnan RSSE Virus[J]. Virologica Sinica, 1992, 7(4).
Citation: HUANG Wen-Li, ZI Deng-Yun, HOU Zong-Liu. Study on the Susceptibility of Animal to Yunnan RSSE Virus .VIROLOGICA SINICA, 1992, 7(4) : 383.

云南森林脑炎病毒的动物敏感性研究

  • 本文对分离自云南的森林脑炎病毒进行了动物敏感性研究,实验证明云南森林脑炎病毒对小白鼠有较强的致病性,三日龄乳鼠无论经脑内、腹腔、皮下接种均能致病、死亡,但毒力较国内森林脑炎病毒标准株低;三周龄小白鼠经鼻腔接种亦能发病致死。对乳大白鼠、幼年豚鼠和金黄色地鼠能引起发病或死亡,病毒抗原定位主要在脑组织。病理检查表明感染的各种动物脑组织均有明显病变。此外,对鸡胚敏感,能引起BHK_(21)、Vero、Vero-E_6等传代细胞及人胚肾、乳猪肾原代细胞的CPE_0结果表明了云南森林脑炎病毒对细胞、动物的致病性与国内森林脑炎病毒标准株相似,仅毒力稍低。

Study on the Susceptibility of Animal to Yunnan RSSE Virus

  • In 1989, 3 strains of Yunnan RSSE virus were isolated from 2 groups of Ixodes Ovatus (T56, T57) and blood of a female patient with fever of unknown infected with YHV, T56v, T57v by intracerebral, intraperitoneal, nasal cavity and subcutaneous inoculation respectively.The incubation period is 3—4 days. The 3 strains of virus could multiply and caused death of chicken embryo, baby rat, young guinea-pig, golden hamster, tupaia belangeri. After infection, the animals showed anorexia, weak, thin, ruffled fur and...

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    Study on the Susceptibility of Animal to Yunnan RSSE Virus

    • 1. Yunnan Institute of Epidemic Diseases Control
    • 2. DaLi 671000

    Abstract: In 1989, 3 strains of Yunnan RSSE virus were isolated from 2 groups of Ixodes Ovatus (T56, T57) and blood of a female patient with fever of unknown infected with YHV, T56v, T57v by intracerebral, intraperitoneal, nasal cavity and subcutaneous inoculation respectively.The incubation period is 3—4 days. The 3 strains of virus could multiply and caused death of chicken embryo, baby rat, young guinea-pig, golden hamster, tupaia belangeri. After infection, the animals showed anorexia, weak, thin, ruffled fur and...

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