A Rapid Detection of Human Papillomavirus 6, 11 DNA in Condyloma Acuminatum

LI Meng-Fa; MA Xiao-Qian; XIE Wei; CHAN Xiang-Nian; JIANG Qing; MAO Yi-Ping; LIU Ji-He; CHANG Bao-Zhu; SUN Jian-Fang; YANG Zhi-Jian

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February 1993

LI Meng-Fa, MA Xiao-Qian, XIE Wei, CHAN Xiang-Nian, JIANG Qing, MAO Yi-Ping, LIU Ji-He, CHANG Bao-Zhu, SUN Jian-Fang and YANG Zhi-Jian. A Rapid Detection of Human Papillomavirus 6, 11 DNA in Condyloma Acuminatum[J]. Virologica Sinica, 1993, 8(1).

Citation: LI Meng-Fa, MA Xiao-Qian, XIE Wei, CHAN Xiang-Nian, JIANG Qing, MAO Yi-Ping, LIU Ji-He, CHANG Bao-Zhu, SUN Jian-Fang, YANG Zhi-Jian. A Rapid Detection of Human Papillomavirus 6, 11 DNA in Condyloma Acuminatum .VIROLOGICA SINICA, 1993, 8(1) : 71.

快速检测尖锐湿疣组织中人乳头瘤病毒6型和11型DNA的研究

1.
南京铁道医学院生物学教研室
2.
中国医学科学院皮肤病研究所
3.
江苏省肿瘤防治研究所病毒室南京

摘要

本文应用聚合酶链反应技术对30例人生殖器尖锐湿疣组织中HPV6,11 DNA的存在进行了检测研究。结果发现HPV6,HPV11 DNA的阳性率分别为60％,90％HPV6,HPV11 DNA双重检出率为53.3％,总阳性率达96.7％,本文结果证实HPV6,11的感染和尖锐湿疣的发生密切相关。本文检测方法具有快速,灵敏、特异性强的优点,为HPVDNA的检测及其分型研究提供了有效的手段。作者还对两例女阴假性湿疣进行PCR扩增,结果似乎不支持女阴假性湿疣的HPV感染的病因学。
- 生殖器尖锐湿疣
- , 女阴假性湿疣
- , 人乳头瘤病毒
- , 聚合酶链反应

A Rapid Detection of Human Papillomavirus 6, 11 DNA in Condyloma Acuminatum

1.
Department of Biology
2.
Nanjing Railway Medical College
3.
Nanjing 210009Institute of Dermatology

Abstract

The polymerase chain reaction (PCR) was applied to identify the human papillomavirus (HPV) 6 and 11 DNA in the spcimens from 30 patients with condyloma acuminatum. The positive percentage of HPV6, HPV11 DNA was 60%, 90%, respectively. 53.3% samples showed the presence of both HPV6 and HPV11 DNA. The total positive percentage was 96.7%. Our result supported the data presented previously that the HPV6 and HPV11 are strongly associated with condyloma acuminatum. The PCR proved to be a rapid, sensitive, highly ...
- Condyloma Acuminatum
- , Atypical Condyloma
- , Human Papillomavirus
- , PCR

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

A Rapid Detection of Human Papillomavirus 6, 11 DNA in Condyloma Acuminatum

1. Department of Biology
2. Nanjing Railway Medical College
3. Nanjing 210009Institute of Dermatology

Abstract: The polymerase chain reaction (PCR) was applied to identify the human papillomavirus (HPV) 6 and 11 DNA in the spcimens from 30 patients with condyloma acuminatum. The positive percentage of HPV6, HPV11 DNA was 60%, 90%, respectively. 53.3% samples showed the presence of both HPV6 and HPV11 DNA. The total positive percentage was 96.7%. Our result supported the data presented previously that the HPV6 and HPV11 are strongly associated with condyloma acuminatum. The PCR proved to be a rapid, sensitive, highly ...