用油桐尺蠖核型多角体病毒（ＢｓＮＰＶ）感染Ｂｓ４８４细胞，对感染后病毒增殖的部分性质及细胞病理变化进行了研究。结果表明：１．病毒子代的增殖在感染后的不同时间具有不同的变化形式，且增殖量与感染剂量具有一定程度的相关，２．病毒感染细胞后１２小时开始在培养物上清检测到明显的胞外病毒粒子；３．就ＢｓＮＰＶ的增殖而言，２４～２６℃是其最佳发育温度；４．病毒感染细胞后的明显病变特征是核内充满多用体，细胞堆积以及细胞体积膨大，同时观察到二类感染细胞，一种核内含较多的多角体，另一种核内则只有几个多用体。

Genome of the characters for the viral multiplication and cytopathic changes in Bs484 cells afterinfection with Buzura suppressaria nuclear polyhedrosis viruses(BsNPV)were reported in thispaper,The results were as follow:1.The multiplication of progeny viruses showed differentchangeable forms in the different times postinfection and the amounts of viral multiplication afterinfection with BsNPV were linearly relating to the viral infective concentration in certain range.2.The extracellular viruses in supernatant from culture were examined at 12 hours postinfection.3.The best fitted developing temperature of BsNPV in Bs484 cells was 24～26℃with regards tothe viral multiplication in vitro.4.The distinct charactistics of cytopathic changes after infectionwith BsNPV mainly included a amounts of polyhedra in nucleus,gathered infected cells and a in-flated cell with big nucleus.In addition,the two types of infected cells were observed in experi-men:a type of nucleus contained many polyhedra,another only had few polyhedr