白纹伊蚊和埃及伊蚊通过吸食病毒液或叮吸有病毒血症的小鸡血后，能感染登革１～４型病毒，并能在蚊体内增萌。对感染雌蚊子１和子２代幼虫、雌性或雄性成虫４５５９只，分１０１批进行了病毒检测。白纹伊蚊子１代的批阳性率：登革１型为１０％（１／１０），２型为２２．２２％（２／９），３型为３３．３３％（４／１２），４型为２８．９５％（１１／３８）；登革１～４型的最低子代感染率依次为０．２０％、０．７１％、０．７０％和０．６３％。子２代对登革４型的批阳性率和最低子代的感染率分别为３５．２９％（６／１７）和０．９３％。登革４型感染埃及伊蚊子１和子２代的最低子代感染率分别为０．６３％和０．６０％。实验表明，白纹伊蚊和埃及伊蚊能经卵传递登革病毒。在本病地方性疫区中，这两种蚊虫在维持登革病毒的自然循环中起重要作用。

Y1 is an imporiant cellular transcriptional regulator which is ubiquitously expressed in vari-ous kinds of cells.The specific binding sites of YY1 protein are found in the flanking sequences ofnlany cellular aiid viral promoters.In the "high risk"huinan papilloniaviruses(HPVs)YY1 works as a traxiscriptional repressor for the viral early gene promoter.In the episomal HPV 16 genomesextracted from cervieal cancers,removal of YY1 binding sites in LCR is a repeated event, resultingin increasing the activity of viral oncogene promoter P97.In order to study the effect of revomal ofYY1 binding sites in LCR on the viral tumorigenicity,HPV16 wild-tny plasmid p1203 was usedas basic sequences,through mltiple-step-clone to construct the new HPV16 plasnuds containingdeleted and mutated LCRs. houence analysis coofirmed that pDV390 had a G to A exchiinge inthe second YY1 site,whereas PDV 1326 and pDV401 contained 115 bp aiid 143 bp deletions in therespective LCRs that revomed 2 and 4 YY1 binding sites.