ZHANG Dong-Hai, SUN Hui and GAO Feng. Studies on Detection of Serum Specific IgA,IgE Antibodies and Circulation Im m une Com plexes in Patients of Hem orrhagic Fever with Renal Syndrom e[J]. Virologica Sinica, 1999, 14(1): 27-31.
Citation: ZHANG Dong-Hai, SUN Hui, GAO Feng. Studies on Detection of Serum Specific IgA,IgE Antibodies and Circulation Im m une Com plexes in Patients of Hem orrhagic Fever with Renal Syndrom e .VIROLOGICA SINICA, 1999, 14(1) : 27-31.

HFRS患者特异性IgA、IgE抗体及其免疫复合物测定

  • 为进一步研究HFRS免疫损伤机制,用ELISA法同步测定了108例不同临床型、不同病日、病期HFRS患者血清中特异性IgA、IgE抗体以及HFRS病毒特异性IgA、IgE型CIC的水平及检出率。发现HFRSIgA型抗体在轻型病例高于中、重型病例;HFRSIgE型抗体及IgE型CIC在重型病例高于中、轻型病例。上述差异在病程早期(发热、休克少尿期,或是3~8病日)尤为突出。IgA型CIC则未见到上述差异。

Studies on Detection of Serum Specific IgA,IgE Antibodies and Circulation Im m une Com plexes in Patients of Hem orrhagic Fever with Renal Syndrom e

  • Detection had been made for the levels of serum specificity IgA, IgE antibodie and specificity of virus antigens circulation immune complexes (CIC) on the different days or phases of illness and clinic types in patients of HFRS. The results showed that the level of specific IgA antibody was higher in slight cases than in middle and severe; specific IgE antibody and its CIC was higher in severe cases than in slight and middle. Those differences were apparent in acute phase (illness phase of fever and shock oilguria, or 3-8 days after illness). But specific CIC IgA types had no diferences

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    Studies on Detection of Serum Specific IgA,IgE Antibodies and Circulation Im m une Com plexes in Patients of Hem orrhagic Fever with Renal Syndrom e

    • 1. Zibo Central Hospital Zibo Shandong Province 255036

    Abstract: Detection had been made for the levels of serum specificity IgA, IgE antibodie and specificity of virus antigens circulation immune complexes (CIC) on the different days or phases of illness and clinic types in patients of HFRS. The results showed that the level of specific IgA antibody was higher in slight cases than in middle and severe; specific IgE antibody and its CIC was higher in severe cases than in slight and middle. Those differences were apparent in acute phase (illness phase of fever and shock oilguria, or 3-8 days after illness). But specific CIC IgA types had no diferences

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