Study on Biological Characters of Sindbis Virus Yunnan Strain

NG Wen---; ZHANG Hal; WANG Jing; ZHANG Yu; ZHOU Guo-linz; M I; SHI Hua; ZI Deng; LIAN Guo

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April 2001

NG Wen---, ZHANG Hal, WANG Jing, ZHANG Yu, ZHOU Guo-linz, M I, SHI Hua, ZI Deng and LIAN Guo. Study on Biological Characters of Sindbis Virus Yunnan Strain[J]. Virologica Sinica, 2001, 16(2): 97-100.

Citation: NG Wen---, ZHANG Hal, WANG Jing, ZHANG Yu, ZHOU Guo-linz, M I, SHI Hua, ZI Deng, LIAN Guo. Study on Biological Characters of Sindbis Virus Yunnan Strain .VIROLOGICA SINICA, 2001, 16(2) : 97-100.

云南辛德毕斯病毒的生物学性状研究

1.
1 云南省流行病防治研究所．云南太理市671000
2.
中国预防医学科学院病毒学研究所，北京 100052

摘要

本文对云南首次分离到的Sindhis病毒进行了滤过试验、耐酸耐醚试验、致细胞病变、动物敏感性试验、血凝特性、空斑和毒力等试验研究．结果符合披膜病毒科的病毒特性。交叉血抑试验和免疫荧光试验．以及空斑减少巾和试验进一步证实为甲病毒属的Sindbis病毒。其空斑纯化株的生物学特性也与原株相符，纯化株的制备为该株病毒分子生物学研究的准确性和一致性提供了条件。云南Sindbis病毒的首次分离具有重要的流行病学意义，其生物学特性研究结果对我省该病的诊断和防治具有重要的指导意义
- 辛德毕斯病毒
- , 生物学特性
- , 空斑纯化

Study on Biological Characters of Sindbis Virus Yunnan Strain

1.
1 Yunnan Institute of Epidemic Disease．~C~ntro[and Research，Dali 671000，China
2.
Institute of ViroZogy Chin~e Academy of Preventive Medicine．Bering 100052．China

Abstract

The biological characters of Sindbis virus strain of Yunnan(YN87448 strain)were studied by the test of the filtration， acid—resistant， ether—resistant， CPE， susceptibility of animal， HA， plague，determination of virus titres，and the cross—HI，cross-lFAT and PRNT as welI The results in— dicated that YN87448 strain belongs to Sindbis virus pha、rirus，Toga~ indae．YN87448 strain virus was plaque purified(PYN87448)．The biological character of PYN87448 strain virus was studied too PYN87448 strain virus will be used in the molecule biological test
- Sindbis virus
- , Biological character
- , Plaque purify

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Study on Biological Characters of Sindbis Virus Yunnan Strain

1. 1 Yunnan Institute of Epidemic Disease．~C~ntro[and Research，Dali 671000，China
2. Institute of ViroZogy Chin~e Academy of Preventive Medicine．Bering 100052．China

Abstract: The biological characters of Sindbis virus strain of Yunnan(YN87448 strain)were studied by the test of the filtration， acid—resistant， ether—resistant， CPE， susceptibility of animal， HA， plague，determination of virus titres，and the cross—HI，cross-lFAT and PRNT as welI The results in— dicated that YN87448 strain belongs to Sindbis virus pha、rirus，Toga~ indae．YN87448 strain virus was plaque purified(PYN87448)．The biological character of PYN87448 strain virus was studied too PYN87448 strain virus will be used in the molecule biological test