Studies on Hantaviras Aerosol Transmission in Laboratory and the Field Sampling

LI Jin—song; LU Jian chun; CHE Feng—xiang; et al

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April 2001

LI Jin—song, LU Jian chun, CHE Feng—xiang, et al and Studies on Hantaviras Aerosol Transmission in Laboratory and the Field Sampling[J]. Virologica Sinica, 2001, 16(2): 124-127.

Citation: LI Jin—song, LU Jian chun, CHE Feng—xiang, et al, . Studies on Hantaviras Aerosol Transmission in Laboratory and the Field Sampling .VIROLOGICA SINICA, 2001, 16(2) : 124-127.

汉坦病毒空气传播感染的实验室和野外采样研究

1.
北京微生物流行病研究所．北京 100071

摘要

本项研究是通过动物实验和现场采样研究救坦病毒气溶腔传播感染。用感染的黑线姬鼠排泄物自然形成的病毒气溶腔进行实验。黑线姬鼠感染后第5天放入离TLd,鼠和乳小鼠．暴露10 d．检测不到抗体．感染后第7天，放入离乳小鼠和乳小鼠．暴露10 d，可以捡测出抗体；黑线姬鼠在暴露15 d时，可以检测出抗体。可见黑线姬鼠感染后．第7天可能是它向体外排毒的一个时问标志．且形成的病毒气溶腔具有感染性。对现场采集的空气样品和收集的打答者佩戴的口罩样品的研究发现，在稻田堆放的稻捆根部和鼠栖息的草窝的空气中每350L空气中和打答场脱粒机附近每96L空气中．古有至少一个具有生物活性的汉坦病毒粒子结合流行病学调查结果，可判定，汉坦病毒经空气传播嗳入感染可能是秋冬季节肾综合征出血热发病的主要传播途径。
- 肾综合征出血热
- , 汉坦病毒
- , 气溶脏
- , 空气传播

Studies on Hantaviras Aerosol Transmission in Laboratory and the Field Sampling

1.
Institute of Microbiology and Eplde,niology，Bering 100071．China

Abstract

Aerosol transmission of Hanlavirus was studled by animal experiments in laboratory and air sampling in the field A agrarlus were subcutaneously inoculated hantavirus，breed in the chamber of the upwind and saved as the sources of virus aerosol Sucking mice，weanling mice and A ．agrarius were put in the chamber of the downwind after the different days of infected A agrarius were breed Two,chambers were parted by the stainless steel net The results suggested that the seventh day could be the time sign that infected A ．agrarius delivered infectious virus aeroso1．The epldemlolng ical in— vestigation of the field suggested that there may have an infectious virus unit at least，in 96L a by threshing machine and 350L air by the nest of A agrarius，respectively．W e believe this study may provide evidence that the aerosol transmission of hantavirus is probably a main route of transmision for hantvlruses in autumn and winter
- Hemorrhagic fever with renal syndrome
- , Hantavirus
- , Aemsol
- , Transmission route

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Studies on Hantaviras Aerosol Transmission in Laboratory and the Field Sampling

1. Institute of Microbiology and Eplde,niology，Bering 100071．China

Abstract: Aerosol transmission of Hanlavirus was studled by animal experiments in laboratory and air sampling in the field A agrarlus were subcutaneously inoculated hantavirus，breed in the chamber of the upwind and saved as the sources of virus aerosol Sucking mice，weanling mice and A ．agrarius were put in the chamber of the downwind after the different days of infected A agrarius were breed Two,chambers were parted by the stainless steel net The results suggested that the seventh day could be the time sign that infected A ．agrarius delivered infectious virus aeroso1．The epldemlolng ical in— vestigation of the field suggested that there may have an infectious virus unit at least，in 96L a by threshing machine and 350L air by the nest of A agrarius，respectively．W e believe this study may provide evidence that the aerosol transmission of hantavirus is probably a main route of transmision for hantvlruses in autumn and winter