A Epidemiological Survey on CM V Infection of Child·bearing Age W omen and Congenital Infection in Wuhan

YAN Ying; fang CHEN; YANG Xiao; KUANG Er-sheng; ZHU Bing; DONG Chang-yuan

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February 2002

YAN Ying, fang CHEN, YANG Xiao, KUANG Er-sheng, ZHU Bing and DONG Chang-yuan. A Epidemiological Survey on CM V Infection of Child·bearing Age W omen and Congenital Infection in Wuhan[J]. Virologica Sinica, 2002, 17(1): 34-37.

Citation: YAN Ying, fang CHEN, YANG Xiao, KUANG Er-sheng, ZHU Bing, DONG Chang-yuan. A Epidemiological Survey on CM V Infection of Child·bearing Age W omen and Congenital Infection in Wuhan .VIROLOGICA SINICA, 2002, 17(1) : 34-37.

育龄妇女和母婴巨细胞病毒感染的流行病学调查

1.
1．武汉大学医学院病毒学研究所．湖北武汉430071
2.
湖北省医学科学院，湖北武祝43oo70

摘要

摘要：我I『1应用ELISA技术和PCR技术对武汉市地区1051名育龄妇女和195对母婴的巨细胞病毒感染进行了血清流行病学调查。结果表明 1246名受检妇女CMVIgM和IgG抗体阳性率分别为3．6％和82．2％。195对母婴有20名产妇尿中CMV-DNA阳性，所生子女中有3名尿中CMV-DNA阳性，相关率为L5％。受检妇女中98名有不良孕产史．其CMV IgM和IgG抗体阳性率与无不良孕产史妇女比较均有显著性差异(p0．01)。
- ELISA
- , PCR
- , 巨细胞病毒
- , 流行病调查

A Epidemiological Survey on CM V Infection of Child·bearing Age W omen and Congenital Infection in Wuhan

1.
1．The Institute of Medical College of WUhan University，W uhan 430071，China
2.
Hubei Medical Science Academy，Wuhan 430070，China

Abstract

Abstract：A survey of CMV seroepidemiology of child—bearing age women and new-born babies and his (her)mother was carried out with EI ISA and PCR technique．The CMV-IgG and IgM antibody posi— tire ratios of 1246 an~yzed women were 82．2％ and 3．6％．respectively．There were 20 mothers and 3 babies with CMV．I)NA ；n their urine among 195 mo thers．There were 98 women who had abnormal borne history in assayed women and their CMV IgG and IgM antibody were ohviously higher than that of normal women(p0．01)．
- ELISA
- , PCR
- , CMV
- , Seroepidemiology

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

A Epidemiological Survey on CM V Infection of Child·bearing Age W omen and Congenital Infection in Wuhan

1. 1．The Institute of Medical College of WUhan University，W uhan 430071，China
2. Hubei Medical Science Academy，Wuhan 430070，China

Abstract: Abstract：A survey of CMV seroepidemiology of child—bearing age women and new-born babies and his (her)mother was carried out with EI ISA and PCR technique．The CMV-IgG and IgM antibody posi— tire ratios of 1246 an~yzed women were 82．2％ and 3．6％．respectively．There were 20 mothers and 3 babies with CMV．I)NA ；n their urine among 195 mo thers．There were 98 women who had abnormal borne history in assayed women and their CMV IgG and IgM antibody were ohviously higher than that of normal women(p0．01)．