GUI Fang, ZHANG Zhuo-ran, ZHENG Cong-long, ZHOU Da-yong, LI Yan, YANG Shu-feng, XU Guo-wang, MING Ping-wen, LIU Zhong-he and YANG Ling. Study of Nanometer Catalyst on Antiviral Action[J]. Virologica Sinica, 2005, 20(1): 70-74.
Citation: GUI Fang, ZHANG Zhuo-ran, ZHENG Cong-long, ZHOU Da-yong, LI Yan, YANG Shu-feng, XU Guo-wang, MING Ping-wen, LIU Zhong-he, YANG Ling. Study of Nanometer Catalyst on Antiviral Action .VIROLOGICA SINICA, 2005, 20(1) : 70-74.

消杀型纳米催化剂抗病毒作用的研究

  • 通讯作者: 张卓然, 
  • 本文探讨112种消杀型纳米催化剂吸附与灭活病毒的功效,为开发新型抗病毒纳米材料提供理论依据。我们将各种纳米催化剂与副流感病毒、人疱疹病毒Ⅰ型、腺病毒1型及5型作用一定时间后,分别以血凝试验及观察CPE变化的方法判断纳米材料对各种病毒的吸附与灭活作用,并在电子显微镜下观察纳米材料对病毒的吸附情况。结果在所检测的112种纳米催化剂中,用血凝试验分别筛选出强吸附力催化剂29 种、中吸附力催化剂36 种、弱吸附力催化剂47种。其中,13 种强吸附力催化剂对副流感病毒的吸附率在87.5%~93.75%之间,并以AB 24的抗病毒效果最好。

Study of Nanometer Catalyst on Antiviral Action

  • Corresponding author: ZHANG Zhuo-ran, 
  • In order to investigate the antiviral activity of 112 kinds of nanomaterials and give theoretical gist for developing new antiviral nanomaterials, we used various nanometer catalysts inhibitory to Parainfluenza virus, Herpes simplex virus types 1, Adenoviruses types 1 and 5 in given time and examined their sorption and virucidal activity through the haemagglutination test and CPE reduction respectively.We also observed their sorption and virucidal activity to viruses under the electron microscope. We found that in the 112 nanometer catalysts tested, the strong, moderate and weak sorption nanometer catalysts were 29,36 and 47 respectively by the haemagglutination test. Among them there were 13 sorts of strong sorption nanometer catalysts whose sorption rate were between 87.5% to 93.75% on parainfluenza virus, and the best was AB-24.

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    Study of Nanometer Catalyst on Antiviral Action

      Corresponding author: ZHANG Zhuo-ran,
    • 1. 

    Abstract: In order to investigate the antiviral activity of 112 kinds of nanomaterials and give theoretical gist for developing new antiviral nanomaterials, we used various nanometer catalysts inhibitory to Parainfluenza virus, Herpes simplex virus types 1, Adenoviruses types 1 and 5 in given time and examined their sorption and virucidal activity through the haemagglutination test and CPE reduction respectively.We also observed their sorption and virucidal activity to viruses under the electron microscope. We found that in the 112 nanometer catalysts tested, the strong, moderate and weak sorption nanometer catalysts were 29,36 and 47 respectively by the haemagglutination test. Among them there were 13 sorts of strong sorption nanometer catalysts whose sorption rate were between 87.5% to 93.75% on parainfluenza virus, and the best was AB-24.

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