Differential susceptibility of immunodeficient mice to MPXV infection and the impact of various inoculation routes

Americo, J.L., Earl, P.L., Moss, B., 2023. Virulence differences of mpox (monkeypox) virus clades I, IIa, and IIb.1 in a small animal model. Proc. Natl. Acad. Sci. U.S.A. 120, e2220415120.
Americo, J.L., Moss, B., Earl, P.L., 2010. Identification of Wild-Derived Inbred Mouse Strains Highly Susceptible to Monkeypox Virus Infection for Use as Small Animal Models. J Virol 84, 8172-8180.
Branche, A., Ramesh, M., Francis, B., 2024. A Narrative Review of Key Risk Factors for Severe Illness Following SARS-CoV-2, Influenza Virus, and Respiratory Syncytial Virus Infection. Infect Dis Ther 14, 39-61.
Bunge, E.M., Hoet, B., Chen, L., Lienert, F., Weidenthaler, H., Baer, L.R., Steffen, R., 2022. The changing epidemiology of human monkeypox-A potential threat? A systematic review. PLoS Negl Trop Dis 16, e0010141.
Chen, D., Yan, Y., Mei, T., Yang, P., Deng, S., Li, Y., Zhao, T., Xin, N., Duan, B., Liang, W., Yang, Y., Zhao, W., Seto, D., Ou, J., Zhang, Q., 2024. Construction and validation of a mouse model for studying severe human adenovirus infections. Virologica Sinica 39, 963-973.
Coleman, D.L., 1978. Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 14, 141-148.
Earl, P.L., Americo, J.L., Moss, B., 2015. Genetic studies of the susceptibility of classical and wild-derived inbred mouse strains to monkeypox virus. Virology 481, 161-165.
Everard, A., Lazarevic, V., Derrien, M., Girard, M., Muccioli, G.G., Neyrinck, A.M., Possemiers, S., Van Holle, A., Francois, P., de Vos, W.M., Delzenne, N.M., Schrenzel, J., Cani, P.D., 2011. Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice. Diabetes 60, 2775-2786.
Geurts, L., Lazarevic, V., Derrien, M., Everard, A., Van Roye, M., Knauf, C., Valet, P., Girard, M., Muccioli, G.G., Francois, P., de Vos, W.M., Schrenzel, J., Delzenne, N.M., Cani, P.D., 2011. Altered gut microbiota and endocannabinoid system tone in obese and diabetic leptin-resistant mice: impact on apelin regulation in adipose tissue. Front Microbiol 2, 149.
Giesbertz, P., Padberg, I., Rein, D., Ecker, J., Hofle, A.S., Spanier, B., Daniel, H., 2015. Metabolite profiling in plasma and tissues of ob/ob and db/db mice identifies novel markers of obesity and type 2 diabetes. Diabetologia 58, 2133-2143.
Hennessee, I., Shelus, V., McArdle, C.E., Wolf, M., Schatzman, S., Carpenter, A., Minhaj, F.S., Petras, J.K., Cash-Goldwasser, S., Maloney, M., Sosa, L., Jones, S.A., Mangla, A.T., Harold, R.E., Beverley, J., Saunders, K.E., Adams, J.N., Stanek, D.R., Feldpausch, A., Pavlick, J., Cahill, M., O’Dell, V., Kim, M., Alarcon, J., Finn, L.E., Goss, M., Duwell, M., Crum, D.A., Williams, T.W., Hansen, K., Heddy, M., Mallory, K., McDermott, D., Cuadera, M.K.Q., Adler, E., Lee, E.H., Shinall, A., Thomas, C., Ricketts, E.K., Koonce, T., Rynk, D.B., Cogswell, K., McLafferty, M., Perella, D., Stockdale, C., Dell, B., Roskosky, M., White, S.L., Davis, K.R., Milleron, R.S., Mackey, S., Barringer, L.A., Bruce, H., Barrett, D., D’Angeli, M., Kocharian, A., Klos, R., Dawson, P., Ellington, S.R., Mayer, O., Godfred-Cato, S., Labuda, S.M., McCormick, D.W., McCollum, A.M., Rao, A.K., Salzer, J.S., Kimball, A., Gold, J.A.W., California Department of Public Health Monkeypox Pediatric Working Group, CDC Monkeypox Pediatric Working Group, 2022. Epidemiologic and Clinical Features of Children and Adolescents Aged <18 Years with Monkeypox - United States, May 17-September 24, 2022. MMWR Morb Mortal Wkly Rep 71, 1407-1411.
Kumar, N., Acharya, A., Gendelman, H.E., Byrareddy, S.N., 2022. The 2022 outbreak and the pathobiology of the monkeypox virus. J Autoimmun 131, 102855.
Laurenson-Schafer, H., Sklenovska, N., Hoxha, A., Kerr, S.M., Ndumbi, P., Fitzner, J., Almiron, M., de Sousa, L.A., Briand, S., Cenciarelli, O., Colombe, S., Doherty, M., Fall, I.S., Garcia-Calavaro, C., Haussig, J.M., Kato, M., Mahamud, A.R., Morgan, O.W., Nabeth, P., Naiene, J.D., Navegantes, W.A., Ogundiran, O., Okot, C., Pebody, R., Matsui, T., Ramirez, H.L.-G., Smallwood, C., Tasigchana, R.F.P., Vaughan, A.M., Williams, G.S., WHO mpox Surveillance and Analytics team, Mala, P.O., Lewis, R.F., Pavlin, B.I., le Polain de Waroux, O., 2023. Description of the first global outbreak of mpox: an analysis of global surveillance data. Lancet Glob Health 11, e1012-e1023.
Osorio, J.E., Iams, K.P., Meteyer, C.U., Rocke, T.E., 2009. Comparison of monkeypox viruses pathogenesis in mice by in vivo imaging. PLoS One 4, e6592.
Zhu, M., Ji, J., Shi, D., Lu, X., Wang, B., Wu, N., Wu, J., Yao, H., Li, L., 2022. Unusual global outbreak of monkeypox: what should we do? Front Med 16, 507-517.