Figure 2个  Table 1个
    • Targets Inhibitors Effective/inhibitory concentration References
      PLpro 5c 9.5 μmol/L(EC50) Baez-Santos et al., 2014
      Mpro 8k1 1.04 μmol/L(IC50) Liu et al., 2014;
      decahydroisoquinolin scaffold 41 63 μmol/L(IC50) Shimamoto et al., 2015
      Cbz-TSAVLQ-CN 1.3-4.6 μmol/L(IC50) Chuck et al., 2014
      NPI52 0.02 μmol/L(EC50) Kim et al., 2015
      Note: EC50: the half maximal effective concentration; IC50: the half maximal inhibitory concentration.

      Table 1.  Inhibitors targeting papain-like protease (PLPro) and main protease (Mpro).