Figure 5个  Table 2个
    • RNA titera CPE
      N130A 2.80 × 107 +
      N207A 1.20 × 107 +
      E173A 5.45 × 107 +
      C4A < 102 (undetectable) -
      C55A < 102 (undetectable) -
      C291A < 102 (undetectable) -
      ΔC < 102 (undetectable) -
      WT 2.60 × 108 +

      Table 1.  Determination of wild type and all mutants titer

    • Mutants P0 (supernatant) P1 (supernatant)
      RNA Copies Ct RNA Copies Ct
      C4A 5.84×103 27.10 < 103
      (undetectable)       		31.54
      C55A 9.09×103 26.42 < 103
      (undetectable)       		31.20
      C291A 2.61×104 24.78 < 103
      (undetectable)       		31.83
      ΔC 2.04×105 21.64 < 103
      (undetectable)       		30.55
      Negative control < 103
      (undetectable)       		34.24 < 103
      (undetectable)       		35.12

      Table 2.  RNA copy analysis for the mutants