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Abdelaal, A., Reda, A., Lashin, B.I., Katamesh, B.E., Brakat, A.M., Al-Manaseer, B.M., Kaur, S., Asija, A., Patel, N.K., Basnyat, S., 2022. Preventing the next pandemic: is live vaccine efficacious against monkeypox, or is there a need for killed virus and mRNA vaccines? Vaccines 10, 1419.

Aklile, B., S., K.D., Stacie, M., Robert, J., F., J.K., E., H.D., W., G.D., 2009. ST-246 Inhibits In Vivo Poxvirus Dissemination, Virus Shedding, and Systemic Disease Manifestation. Antimicrob. Agents Chemother. 53, 4999-5009. https://doi.org/10.1128/aac.00678-09.

ANDREWES, C.H., ELFORD, W.J., 1947. Infections ectromelia; experiments on interference and immunization. Br. J. Exp. Pathol. 28, 278-285.

Artenstein, A.W., Johnson, C., Marbury, T.C., Morrison, D., Blum, P.S., Kemp, T., Nichols, R., Balser, J.P., Currie, M., Monath, T.P., 2005. A novel, cell culture-derived smallpox vaccine in vaccinia-naive adults. Vaccine 23, 3301-3309.

Avril, A., Guillier, S., Rasetti-Escargueil, C., 2024. Development of Effective Medical Countermeasures Against the Main Biowarfare Agents: The Importance of Antibodies. Microorganisms. https://doi.org/10.3390/microorganisms12122622.

Benson, G., 1999. Tandem repeats finder: a program to analyze DNA sequences. Nucleic Acids Res. 27, 573-580.

Buckingham, S., 2003. Bioinformatics: programmed for success. Nature 425, 209-211.

CAMCIOGLU, Y., 2024. Old stories, new cases. Viral infectious diseases and children’s health. Glob. Pediatr. 9, 100210.

Chen, N., Danila, M.I., Feng, Z., Buller, R.M.L., Wang, C., Han, X., Lefkowitz, E.J., Upton, C., 2003. The genomic sequence of ectromelia virus, the causative agent of mousepox. Virology 317, 165-186. https://doi.org/10.1016/S0042-6822(03)00520-8.

Esteban, D., Parker, S., Schriewer, J., Hartzler, H., Buller, R.M., 2012. Mousepox, A Small Animal Model of Smallpox BT - Vaccinia Virus and Poxvirology: Methods and Protocols, in: Isaacs, S.N. (Ed.), . Humana Press, Totowa, NJ, pp. 177-198. https://doi.org/10.1007/978-1-61779-876-4_11.

Fang, Q., Yang, L., Zhu, W., Liu, L., Wang, H., Yu, W., Xiao, G., Tien, P., Zhang, L., Chen, Z., 2005. Host range, growth property, and virulence of the smallpox vaccine: vaccinia virus Tian Tan strain. Virology 335, 242-251.

FENNER, F., 1949. Studies in mousepox, infectious ectromelia of mice; the effect of the age of the host upon the response to infection. Aust. J. Exp. Biol. Med. Sci. 27, 45-53. https://doi.org/10.1038/icb.1949.4.

Francoise, M., Leonor, P., Oceane, S., Fabrice, B., Edwin, D., Isabelle, S.-C., Alain, V., G., D.B., 2015. Viral Semaphorin Inhibits Dendritic Cell Phagocytosis and Migration but Is Not Essential for Gammaherpesvirus-Induced Lymphoproliferation in Malignant Catarrhal Fever. J. Virol. 89, 3630-3647. https://doi.org/10.1128/jvi.03634-14.

Gardner, J.D., Tscharke, D.C., Reading, P.C., Smith, G.L., 2001. Vaccinia virus semaphorin A39R is a 50-55 kDa secreted glycoprotein that affects the outcome of infection in a murine intradermal model. J. Gen. Virol. 82, 2083-2093. https://doi.org/10.1099/0022-1317-82-9-2083.

Grosenbach, D.W., Jordan, R., Hruby, D.E., 2011. Development of the small-molecule antiviral ST-246 as a smallpox therapeutic. Future Virol. 6, 653-671. https://doi.org/10.2217/fvl.11.27.

Gruber, C.E.M., Giombini, E., Selleri, M., Tausch, S.H., Andrusch, A., Tyshaieva, A., Cardeti, G., Lorenzetti, R., De Marco, L., Carletti, F., 2018. Whole genome characterization of Orthopoxvirus (OPV) Abatino, a zoonotic virus representing a putative novel clade of Old World orthopoxviruses. Viruses 10, 546.

Huo, S., Wu, L., Huang, B., Liu, N., Sun, J., Ye, F., Deng, Y., Chen, J., Gong, L., Zhu, W., Xu, Z., Tan, W., 2024. Identification of the VP37 pocket of monkeypox virus as a promising target for pan-orthopoxvirus inhibitors through virtual screening and antiviral assays. Emerg. Microbes Infect. 13, 2373309. https://doi.org/10.1080/22221751.2024.2373309.

Jennifer, S., Mark, B.R., Jill, S., Cheri, W., E., S.J., Scott, P., 2010. A Mouse Model of Lethal Infection for Evaluating Prophylactics and Therapeutics against Monkeypox Virus . J. Virol. 84, 3909-3920. https://doi.org/10.1128/jvi.02012-09.

Katoh, K., Standley, D.M., 2013. MAFFT multiple sequence alignment software version 7: improvements in performance and usability. Mol. Biol. Evol. 30, 772-780.

Koren, S., Walenz, B.P., Berlin, K., Miller, J.R., Bergman, N.H., Phillippy, A.M., 2017. Canu: scalable and accurate long-read assembly via adaptive k-mer weighting and repeat separation. Genome Res. 27, 722-736.

Kvansakul, M., Yang, H., Fairlie, W.D., Czabotar, P.E., Fischer, S.F., Perugini, M.A., Huang, D.C.S., Colman, P.M., 2008. Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands. Cell Death Differ. 15, 1564-1571. https://doi.org/10.1038/cdd.2008.83.

Liu, H., Juo, Z.S., Shim, A.H.-R., Focia, P.J., Chen, X., Garcia, K.C., He, X., 2010. Structural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1. Cell 142, 749-761. https://doi.org/10.1016/j.cell.2010.07.040.

Lorenz, R., Bernhart, S.H., Honer zu Siederdissen, C., Tafer, H., Flamm, C., Stadler, P.F., Hofacker, I.L., 2011. ViennaRNA Package 2.0. Algorithms Mol. Biol. 6, 1-14.

Mavian, C., Lopez-Bueno, A., Bryant, N.A., Seeger, K., Quail, M.A., Harris, D., Barrell, B., Alcami, A., 2014. The genome sequence of ectromelia virus Naval and Cornell isolates from outbreaks in North America. Virology 462-463, 218-226. https://doi.org/10.1016/j.virol.2014.06.010.

Mavian, C., Lopez-Bueno, A., Martin, R., Nitsche, A., Alcami, A., 2021. Comparative Pathogenesis, Genomics and Phylogeography of Mousepox. Viruses. https://doi.org/10.3390/v13061146.

Mehta, N., Taylor, J., Quilty, D., Barry, M., 2015. Ectromelia virus encodes an anti-apoptotic protein that regulates cell death. Virology 475, 74-87. https://doi.org/10.1016/j.virol.2014.10.023.

Mendez-Rios, J.D., Martens, C.A., Bruno, D.P., Porcella, S.F., Zheng, Z.-M., Moss, B., 2012. Genome Sequence of Erythromelalgia-Related Poxvirus Identifies it as an Ectromelia Virus Strain. PLoS One 7, e34604.

Merchlinsky, M., Moss, B., 1989. Nucleotide sequence required for resolution of the concatemer junction of vaccinia virus DNA. J. Virol. 63, 4354-4361. https://doi.org/10.1128/jvi.63.10.4354-4361.1989.

Minh, B.Q., Schmidt, H.A., Chernomor, O., Schrempf, D., Woodhams, M.D., Von Haeseler, A., Lanfear, R., 2020. IQ-TREE 2: new models and efficient methods for phylogenetic inference in the genomic era. Mol. Biol. Evol. 37, 1530-1534.

Overholt, W.A., Holzer, M., Geesink, P., Diezel, C., Marz, M., Kusel, K., 2020. Inclusion of Oxford Nanopore long reads improves all microbial and viral metagenome-assembled genomes from a complex aquifer system. Environ. Microbiol. 22, 4000-4013.

Parker, S., Chen, N.G., Foster, S., Hartzler, H., Hembrador, E., Hruby, D., Jordan, R., Lanier, R., Painter, G., Painter, W., Sagartz, J.E., Schriewer, J., Mark Buller, R., 2012. Evaluation of disease and viral biomarkers as triggers for therapeutic intervention in respiratory mousepox - an animal model of smallpox. Antivir. Res. 94, 44-53. https://doi.org/10.1016/j.antiviral.2012.02.005.

Parker, S., Siddiqui, A.M., Painter, G., Schriewer, J., Buller, R.M., 2010. Ectromelia virus infections of mice as a model to support the licensure of anti-orthopoxvirus therapeutics. Viruses 2, 1918-1932. https://doi.org/10.3390/v2091918.

Parker, S., Touchette, E., Oberle, C., Almond, M., Robertson, A., Trost, L.C., Lampert, B., Painter, G., Buller, R.M., 2008. Efficacy of therapeutic intervention with an oral ether-lipid analogue of cidofovir (CMX001) in a lethal mousepox model. Antivir. Res. 77, 39-49. https://doi.org/10.1016/j.antiviral.2007.08.003.

Perez, P., Marin, M.Q., Lazaro-Frias, A., Sorzano, C.O.S., Gomez, C.E., Esteban, M., Garcia-Arriaza, J., 2020. Deletion of Vaccinia Virus A40R Gene Improves the Immunogenicity of the HIV-1 Vaccine Candidate MVA-B. Vaccines. https://doi.org/10.3390/vaccines8010070.

C, Q.D., L., B.R.M., Scott, P., A., K.K., E., H.D., Robert, J., R., K.E., 2007. Efficacy of Delayed Treatment with ST-246 Given Orally against Systemic Orthopoxvirus Infections in Mice. Antimicrob. Agents Chemother. 51, 689-695. https://doi.org/10.1128/aac.00879-06.

Riaz, N., Leung, P., Barton, K., Smith, M.A., Carswell, S., Bull, R., Lloyd, A.R., Rodrigo, C., 2021. Adaptation of Oxford Nanopore technology for hepatitis C whole genome sequencing and identification of within-host viral variants. BMC Genomics 22, 1-12.

Stewart, E.J., Madden, R., Paul, G., Taddei, F., 2005. Aging and Death in an Organism That Reproduces by Morphologically Symmetric Division. PLOS Biol. 3, e45.

Taylor, J.M., Quilty, D., Banadyga, L., Barry, M., 2006. The Vaccinia Virus Protein F1L Interacts with Bim and Inhibits Activation of the Pro-apoptotic Protein Bax ∗. J. Biol. Chem. 281, 39728-39739. https://doi.org/10.1074/jbc.M607465200.

Turner, P.C., Moyer, R.W., 2002. Poxvirus immune modulators: functional insights from animal models. Virus Res. 88, 35-53. https://doi.org/10.1016/S0168-1702(02)00119-3.

Tutar, Y., 2012. Pseudogenes. Int. J. Genomics 2012, 424526. https://doi.org/10.1155/2012/424526.

Walzer, T., Galibert, L., Smedt, T. De, 2005. Poxvirus semaphorin A39R inhibits phagocytosis by dendritic cells and neutrophils. Eur. J. Immunol. 35, 391-398. https://doi.org/10.1002/eji.200425669.

Wang, H., Yin, P., Zheng, T., Qin, L., Li, S., Han, P., Qu, X., Wen, J., Ding, H., Wu, J., 2024. Rational design of a ‘two-in-one’immunogen DAM drives potent immune response against mpox virus. Nat. Immunol. 25, 307-315.

Wang, J., Liu, X., Zhu, Q., Wu, Q., Tang, S., Zhang, L., Fan, Z., Hu, Z., Wang, H., Deng, F., Shen, S., 2021. Identification, Isolation, and Characterization of an Ectromelia Virus New Strain from an Experimental Mouse. Virol. Sin. 36, 155-158. https://doi.org/10.1007/s12250-020-00263-w.

Wasilenko, S.T., Stewart, T.L., Meyers, A.F.A., Barry, M., 2003. Vaccinia virus encodes a previously uncharacterized mitochondrial-associated inhibitor of apoptosis. Proc. Natl. Acad. Sci. 100, 14345 LP - 14350. https://doi.org/10.1073/pnas.2235583100.

Wilcock, D., Duncan, S.A., Traktman, P., Zhang, W.-H., Smith, G.L., 1999. The vaccinia virus A40R gene product is a nonstructural, type II membrane glycoprotein that is expressed at the cell surface. J. Gen. Virol. 80, 2137-2148. https://doi.org/10.1099/0022-1317-80-8-2137.

Wright, I.A., Delaney, K.E., Katusiime, M.G.K., Botha, J.C., Engelbrecht, S., Kearney, M.F., van Zyl, G.U., 2021. NanoHIV: a bioinformatics pipeline for producing accurate, near full-length HIV proviral genomes sequenced using the oxford nanopore technology. Cells 10, 2577.

Zheng, Z.-M., Specter, S., Zhang, J.-H., Friedman, H., Zhu, W.-P., 1992. Further characterization of the biological and pathogenic properties of erythromelalgia-related poxviruses. J. Gen. Virol. 73, 2011-2019. https://doi.org/10.1099/0022-1317-73-8-2011.

Zheng, Z.M., Specter, S., Friedman, H., 1991. Presence of specific IgG antibody to the A type inclusions of erythromelalgia-related poxvirus in the sera of patients with epidemic erythromelalgia. Arch. Dermatol. Res. 283, 535-536. https://doi.org/10.1007/BF00371930.

Zheng, Z.M., Zhang, J.H., Hu, J.M., Liu, S.F., Zhu, W.P., 1988. Poxviruses isolated from epidemic erythromelalgia in China. Lancet (London, England). https://doi.org/10.1016/s0140-6736(88)90372-8.