Figure 7个 Table 1个

Genotype	Segment	E		NS2A			NS2B	NS3			NS4A	NS4B	NS5
Genotype	Domain	^aDI		DII	/		/	Pro	Hel		/	TM	MTase	RdRp
^/	^bLocation(nt)	1399	1434	1540	4080	4125	4429	4876	5065	5817	6390	7144	8182	9112	9207
^/	^cLocation(aa)	155	166	202	191	206	97	119	182	332	5	107	151	461	492
Cosmopolitan	1D4-5-SP	^d(A)Thr	(A)P	(A)Lys	(C)L	(G)K	(C)R	(A)Asn	(A)Ile	(G)V	(T)N	(C)Leu	(T)L	(C)Leu	(C)Asp
	8H2-7-LP	(G)Ala	(G)P	(G)Glu	(T)L	(A)K	(A)R	(G)Asp	(G)Val	(C)V	(C)N	(T)Phe	(C)L	(A) Ile	(A)Glu
	^eAY037116	–	(C)P	(G)Glu	–	–	(A)R	–	–	(C)V	–	–	–	–	–
Asian I	DQ181801	–	–	(G)Glu	–	–	(A)R	–	–	(T)V	(C)N	–	–	–	–
Asian Ⅱ	MK506263	–	–	(G)Glu	–	–	(A)R	–	–	(C)V	(C)N	–	–	–	–
Asian/American	M29095	–	–	(G)Glu	–	–	(A)R	–	–	(T)V	(C)N	–	–	–	–
American	AY702040	–	–	(G)Glu	–	–	(A)R	–	–	(T)V	(C)N	–	–	–	(T)Asp
Sylvatic	EF105378	–	(C)P	(G)Glu	–	(A)K	(A)R	–	–	(T)V	–	–	(C)L	–	(T)Asp
^aDⅠ, DⅡ domain Ⅰ, Ⅱ of E protein ectodomain, Pro Protease, Hel Helicase, TM Transmembrane, MTase, methyltransferase; RdRp, RNA-dependent RNA polymerase; ^bLocation of nucleotide variation in the whole viral genomes; ^cLocation of both synonymous and nonsynonymous variation sites on amino acid sequences of each viral protein; ^dNonsynonymous variations were presented with three-letter amino acid codes; ^eRepresentative strains from each genotype were selected from sequences analyzed in Fig. 2, and listed in table with their access number for comparison. "–" means the nucleotide and residue are identical to the first strain 1D4-5-SP.

Table 1. Sequence variation between 8H2-7-LP and 1D4-5-SP.