-
Beug ST, Cheung HH, LaCasse EC, Korneluk RG, 2012: Modulation of immune signalling by inhibitors of apoptosis[J]. Trends Immunol, 33, 535-545. doi: 10.1016/j.it.2012.06.004
-
Block TM, Alter H, Brown N, Brownstein A, Brosgart C, Chang KM, Chen PJ, Cohen C, El-Serag H, Feld J, Gish R, Glenn J, Greten TF, Guo JT, Hoshida Y, Kowdley KV, Li W, Lok AS, McMahon B, Mehta A, Perrillo R, Rice CM, Rinaudo J, Schinazi RF, Shetty K, 2018: Research priorities for the discovery of a cure for chronic hepatitis B: report of a workshop[J]. Antivir Res, 150, 93-100. doi: 10.1016/j.antiviral.2017.12.006
-
Chesi M, Mirza NN, Garbitt VM, Sharik ME, Dueck AC, Asmann YW, Akhmetzyanova I, Kosiorek HE, Calcinotto A, Riggs DL, Keane N, Ahmann GJ, Morrison KM, Fonseca R, Lacy MQ, Dingli D, Kumar SK, Ailawadhi S, Dispenzieri A, Buadi F, Gertz MA, Reeder CB, Lin Y, Chanan-Khan AA, Stewart AK, Fooksman D, Bergsagel PL, 2016: IAP antagonists induce antitumor immunity in multiple myeloma[J]. Nat Med, 22, 1411-1420. doi: 10.1038/nm.4229
-
Ebert G, Allison C, Preston S, Cooney J, Toe JG, Stutz MD, Ojaimi S, Baschuk N, Nachbur U, Torresi J, Silke J, Begley CG, Pellegrini M, 2015a: Eliminating hepatitis B by antagonizing cellular inhibitors of apoptosis[J]. Proc Natl Acad Sci USA, 112, 5803-5808. doi: 10.1073/pnas.1502400112
-
Ebert G, Preston S, Allison C, Cooney J, Toe JG, Stutz MD, Ojaimi S, Scott HW, Baschuk N, Nachbur U, Torresi J, Chin R, Colledge D, Li X, Warner N, Revill P, Bowden S, Silke J, Begley CG, Pellegrini M, 2015b: Cellular inhibitor of apoptosis proteins prevent clearance of hepatitis B virus[J]. Proc Natl Acad Sci USA, 112, 5797-5802. doi: 10.1073/pnas.1502390112
-
Estornes Y, Bertrand MJ, 2015: IAPs, regulators of innate immunity and inflammation[J]. Semin Cell Dev Biol, 39, 106-114. doi: 10.1016/j.semcdb.2014.03.035
-
European Association for the Study of the Liver , 2017: EASL 2017 clinical practice guidelines on the management of hepatitis B virus infection[J]. J Hepatol, 67, 370-398. doi: 10.1016/j.jhep.2017.03.021
-
Guidotti LG, Inverso D, Sironi L, Di Lucia P, Fioravanti J, Ganzer L, Fiocchi A, Vacca M, Aiolfi R, Sammicheli S, Mainetti M, Cataudella T, Raimondi A, Gonzalez-Aseguinolaza G, Protzer U, Ruggeri ZM, Chisari FV, Isogawa M, Sitia G, Iannacone M, 2015: Immunosurveillance of the liver by intravascular effector CD8(+) T cells[J]. Cell, 161, 486-500. doi: 10.1016/j.cell.2015.03.005
-
Li N, Feng L, Han HQ, Yuan J, Qi XK, Lian YF, Kuang BH, Zhang YC, Deng CC, Zhang HJ, Yao YY, Xu M, He GP, Zhao BC, Gao L, Feng QS, Chen LZ, Yang L, Yang D, Zeng YX, 2016: A novel Smac mimetic APG-1387 demonstrates potent antitumor activity in nasopharyngeal carcinoma cells by inducing apoptosis[J]. Cancer Lett, 381, 14-22. doi: 10.1016/j.canlet.2016.07.008
-
Li BX, Wang HB, Qiu MZ, Luo QY, Yi HJ, Yan XL, Pan WT, Yuan LP, Zhang YX, Xu JH, Zhang L, Yang DJ, 2018: Novel smac mimetic APG-1387 elicits ovarian cancer cell killing through TNF-alpha, Ripoptosome and autophagy mediated cell death pathway[J]. J Exp Clin Cancer Res, 37, 53-. doi: 10.1186/s13046-018-0703-9
-
Lok AS, Zoulim F, Dusheiko G, Ghany MG, 2017: Hepatitis B cure: from discovery to regulatory approval[J]. Hepatology, 66, 1296-1313. doi: 10.1002/hep.29323
-
Ott JJ, Stevens GA, Groeger J, Wiersma ST, 2012: Global epidemiology of hepatitis B virus infection: new estimates of age-specific HBsAg seroprevalence and endemicity[J]. Vaccine, 30, 2212-2219. doi: 10.1016/j.vaccine.2011.12.116
-
Pan W, Luo Q, Yan X, Yuan L, Yi H, Zhang L, Li B, Zhang Y, Sun J, Qiu MZ, Yang DJ, 2018: A novel SMAC mimetic APG-1387 exhibits dual antitumor effect on HBV-positive hepatocellular carcinoma with high expression of cIAP2 by inducing apoptosis and enhancing innate anti-tumor immunity[J]. Biochem Pharmacol, 154, 127-135. doi: 10.1016/j.bcp.2018.04.020
-
Sarin SK, Kumar M, Lau GK, Abbas Z, Chan HL, Chen CJ, Chen DS, Chen HL, Chen PJ, Chien RN, Dokmeci AK, Gane E, Hou JL, Jafri W, Jia J, Kim JH, Lai CL, Lee HC, Lim SG, Liu CJ, Locarnini S, Al Mahtab M, Mohamed R, Omata M, Park J, Piratvisuth T, Sharma BC, Sollano J, Wang FS, Wei L, Yuen MF, Zheng SS, Kao JH, 2016: Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update[J]. Hepatol Int, 10, 1-98.
-
Tang LSY, Covert E, Wilson E, Kottilil S, 2018: Chronic hepatitis B infection: a review[J]. JAMA, 319, 1802-1813. doi: 10.1001/jama.2018.3795
-
Terrault NA, Lok ASF, McMahon BJ, Chang KM, Hwang JP, Jonas MM, Brown RS Jr, Bzowej NH, Wong JB, 2018: Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance[J]. Hepatology, 67, 1560-1599. doi: 10.1002/hep.v67.4
-
Wang Z, Ni J, Li J, Shi B, Xu Y, Yuan Z, 2011: Inhibition of hepatitis B virus replication by cIAP2 involves accelerating the ubiquitin-proteasome-mediated destruction of polymerase[J]. J Virol, 85, 11457-11467. doi: 10.1128/JVI.00879-11
-
Xu R, Li Y, Ji J, Qiu M, Zhang Y, Liu W, Tian X, Li S, Wang H, Wang F, Zhang D, Wang F, Wang Z, Luo H, Zou B, Wang D, Ren C, Jin Y, Zhai Y, Yang D, 2018: A phase Ⅰ study of a novel IAP inhibitor APG-1387 in patients with advanced solid tumors[J]. J Clin Oncol, 36, 2593-. doi: 10.1200/JCO.2018.36.15_suppl.2593
-
Yuen MF, Chen DS, Dusheiko GM, Janssen HLA, Lau DTY, Locarnini SA, Peters MG, Lai CL, 2018: Hepatitis B virus infection[J]. Nat Rev Dis Primers, 4, 18035-. doi: 10.1038/nrdp.2018.35