Figure 4个  Table 1个
    • NA ConstructOseltamivir
      (nmol/L)      		Luciferase Activity
      (RLU)      		HA
      (U/mL)      		4-MUNANA Release
      (a.u.)
      Parental01.8(±0.01)×107323.1(±0.2)×104
      11.8(±0.06)×10741.4(±0.1)×104
      101.1(±0.2)×10725.6(±0.4)×103
      1001.6(±0.09)×10501.0(±0.04)×103
      10002.2(±1.3)×10304.9(±0.3)×102
      H274Y01.8(±0.09)×10781.0(±0.1)×104
      11.6(±0.05)×107166.4(±0.4)×103
      101.5(±0.1)×107166.0(±0.4)×103
      1001.8(±0.02)×10785.3(±0.1)×103
      10001.1(±0.3)×10641.9(±0.2)×103
      N294S01.8(±0.05)×10741.1(±0.06)×104
      11.8(±0.03)×10741.2(±0.07)×104
      101.8(±0.03)×10741.1(±0.1)×104
      1004.0(±1.2)×10645.7(±0.2)×103
      10002.2(±0.7)×10501.3(±0.06)×103
      D198N05.7(±2.1)×10527.0(±0.5)×102
      12.6(±0.4)×10526.6(±0.2)×102
      104.0(±1.3)×10405.1(±0.2)×102
      1001.6(±0.2)×10403.3(±0.2)×102
      10001.1(±0.3)×10402.5(±0.08)×102
      I222L01.5(±0.2)×10785.1(±0.4)×103
      11.5(±0.2)×10784.4(±0.2)×103
      101.1(±0.1)×10723.6(±0.2)×103
      1001.4(±0.3)×10501.1(±0.2)×103
      10004.1(±1.5)×10403.1(±0.08)×102
      E119V02.5(±1.8)×10405.7(±0.7)×102
      13.3(±2.9)×10404.0(±0.2)×102
      107.6(±4.3)×10404.3(±0.1)×102
      1002.0(±2.6)×10403.5(±0.3)×102
      10007.4(±0.3)×10302.7(±0.5)×102
      R292K04.9(±1.4)×10306.4(±0.3)×102
      11.1(±0.1)×10404.1(±0.2)×102
      108.1(±3.8)×10304.3(±0.5)×102
      1004.7(±0.53)×10304.1(±0.7)×102
      10001.4(±0.32)×10404.6(±0.1)×102

      Table 1.  Summary of Characteristics of NA mutants