-
Asim M, Jiang S, Yi L, Chen W, Sun L, Zhao L, Khan Khattak MN, Tu J, Lin L, 2017: Glutamine is required for red-spotted grouper nervous necrosis virus replication via replenishing the tricarboxylic acid cycle[J]. Virus Res, 227, 245-248. doi: 10.1016/j.virusres.2016.11.007
-
Baker JC, Yan X, Peng T, Kasten S, Roche TE, 2000: Marked differences between two isoforms of human pyruvate dehydrogenase kinase[J]. J Biol Chem, 275, 15773-15781. doi: 10.1074/jbc.M909488199
-
Barban S, Schulze HO, 1961: The effects of 2-deoxyglucose on the growth and metabolism of cultured human cells[J]. J Biol Chem, 236, 1887-1890. doi: 10.1016/S0021-9258(18)64100-6
-
Chase GP, Rameix-Welti MA, Zvirbliene A, Zvirblis G, Gotz V, Wolff T, Naffakh N, Schwemmle M, 2011: Influenza virus ribonucleoprotein complexes gain preferential access to cellular export machinery through chromatin targeting[J]. PLoS Pathog, 7, e1002187-. doi: 10.1371/journal.ppat.1002187
-
Chen IT, Aoki T, Huang YT, Hirono I, Chen TC, Huang JY, Chang GD, Lo CF, Wang HC, 2011: White spot syndrome virus induces metabolic changes resembling the warburg effect in shrimp hemocytes in the early stage of infection[J]. J Virol, 85, 12919-12928. doi: 10.1128/JVI.05385-11
-
Chuang C, Prasanth KR, Nagy PD, 2017: The Glycolytic Pyruvate Kinase Is Recruited Directly into the Viral Replicase Complex to Generate ATP for RNA Synthesis[J]. Cell Host Microbe, 22, 639-652. doi: 10.1016/j.chom.2017.10.004
-
Crane CA, Austgen K, Haberthur K, Hofmann C, Moyes KW, Avanesyan L, Fong L, Campbell MJ, Cooper S, Oakes SA, Parsa AT, Lanier LL, 2014: Immune evasion mediated by tumor-derived lactate dehydrogenase induction of NKG2D ligands on myeloid cells in glioblastoma patients[J]. Proc Natl Acad Sci U S A, 111, 12823-12828. doi: 10.1073/pnas.1413933111
-
Elwood JC, 1968: Effect of oxamate on glycolysis and respiration in sarcoma 37 ascites cells[J]. Cancer Res, 28, 2056-2060.
-
Fontaine KA, Camarda R, Lagunoff M, 2014: Vaccinia virus requires glutamine but not glucose for efficient replication[J]. J Virol, 88, 4366-4374. doi: 10.1128/JVI.03134-13
-
Fontaine KA, Sanchez EL, Camarda R, Lagunoff M, 2015: Dengue virus induces and requires glycolysis for optimal replication[J]. J Virol, 89, 2358-2366. doi: 10.1128/JVI.02309-14
-
Fulda S, Debatin KM, 2007: HIF-1-regulated glucose metabolism: a key to apoptosis resistance?[J]. Cell Cycle, 6, 790-792. doi: 10.4161/cc.6.7.4084
-
Genzel Y, Behrendt I, Konig S, Sann H, Reichl U, 2004: Metabolism of MDCK cells during cell growth and influenza virus production in large-scale microcarrier culture[J]. Vaccine, 22, 2202-2208. doi: 10.1016/j.vaccine.2003.11.041
-
Gershon TR, Crowther AJ, Tikunov A, Garcia I, Annis R, Yuan H, Miller CR, Macdonald J, Olson J, Deshmukh M, 2013: Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma[J]. Cancer Metab, 1, 2-. doi: 10.1186/2049-3002-1-2
-
Han F, Xue M, Chang Y, Li X, Yang Y, Sun B, Chen L, 2017: Triptolide suppresses glomerular mesangial cell proliferation in diabetic nephropathy is associated with inhibition of PDK1/Akt/mTOR pathway[J]. Int J Biol Sci, 13, 1266-1275. doi: 10.7150/ijbs.20485
-
Herold S, Becker C, Ridge KM, Budinger GR, 2015: Influenza virus-induced lung injury: pathogenesis and implications for treatment[J]. Eur Respir J, 45, 1463-1478. doi: 10.1183/09031936.00186214
-
Hindie V, Stroba A, Zhang H, Lopez-Garcia LA, Idrissova L, Zeuzem S, Hirschberg D, Schaeffer F, Jorgensen TJ, Engel M, Alzari PM, Biondi RM, 2009: Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1[J]. Nat Chem Biol, 5, 758-764. doi: 10.1038/nchembio.208
-
Hsieh YC, Chen YM, Li CY, Chang YH, Liang SY, Lin SY, Lin CY, Chang SH, Wang YJ, Khoo KH, Aoki T, Wang HC, 2015: To complete its replication cycle, a shrimp virus changes the population of long chain fatty acids during infection via the PI3K-Akt-mTOR-HIF1alpha pathway[J]. Dev Comp Immunol, 53, 85-95. doi: 10.1016/j.dci.2015.06.001
-
Hurt AC, 2014: The epidemiology and spread of drug resistant human influenza viruses[J]. Curr Opin Virol, 8, 22-29. doi: 10.1016/j.coviro.2014.04.009
-
Iuliano AD, Roguski KM, Chang HH, Muscatello DJ, Palekar R, Tempia S, Cohen C, Gran JM, Schanzer D, Cowling BJ, Wu P, Kyncl J, Ang LW, Park M, Redlberger-Fritz M, Yu H, Espenhain L, Krishnan A, Emukule G, van Asten L, Pereira da Silva S, Aungkulanon S, Buchholz U, Widdowson MA, Bresee JS, Global Seasonal Influenza-associated Mortality Collaborator N, 2018: Estimates of global seasonal influenza-associated respiratory mortality: a modelling study[J]. Lancet, 391, 1258-1300. doi: 10.1016/S0140-6736(18)30497-5
-
Iwasaki A, Pillai PS, 2014: Innate immunity to influenza virus infection[J]. Nat Rev Immunol, 14, 315-328. doi: 10.1038/nri3665
-
Koyuncu E, Purdy JG, Rabinowitz JD, Shenk T, 2013: Saturated very long chain fatty acids are required for the production of infectious human cytomegalovirus progeny[J]. PLoS Pathog, 9, e1003333-. doi: 10.1371/journal.ppat.1003333
-
Levy PL, Duponchel S, Eischeid H, Molle J, Michelet M, Diserens G, Vermathen M, Vermathen P, Dufour JF, Dienes HP, Steffen HM, Odenthal M, Zoulim F, Bartosch B, 2017: Hepatitis C virus infection triggers a tumor-like glutamine metabolism[J]. Hepatology, 65, 789-803. doi: 10.1002/hep.28949
-
Li TC, Chan MC, Lee N, 2015: Clinical Implications of Antiviral Resistance in Influenza[J]. Viruses, 7, 4929-4944. doi: 10.3390/v7092850
-
Matrosovich M, Matrosovich T, Garten W, Klenk HD, 2006: New low-viscosity overlay medium for viral plaque assays[J]. Virol J, 3, 63-. doi: 10.1186/1743-422X-3-63
-
Mazzon M, Castro C, Thaa B, Liu L, Mutso M, Liu X, Mahalingam S, Griffin JL, Marsh M, McInerney GM, 2018: Alphavirus-induced hyperactivation of PI3K/AKT directs pro-viral metabolic changes[J]. PLoS Pathog, 14, e1006835-. doi: 10.1371/journal.ppat.1006835
-
Michelakis ED, Webster L, Mackey JR, 2008: Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer[J]. Br J Cancer, 99, 989-994. doi: 10.1038/sj.bjc.6604554
-
Miyake Y, Ishii K, Honda A, 2017: Influenza virus infection induces host pyruvate kinase M which interacts with Viral RNA-dependent RNA polymerase[J]. Front Microbiol, 8, 162-.
-
Muller KH, Kakkola L, Nagaraj AS, Cheltsov AV, Anastasina M, Kainov DE, 2012: Emerging cellular targets for influenza antiviral agents[J]. Trends Pharmacol Sci, 33, 89-99. doi: 10.1016/j.tips.2011.10.004
-
Passalacqua KD, Lu J, Goodfellow I, Kolawole AO, Arche JR, Maddox RJ, Carnahan KE, O'Riordan MXD, Wobus CE, 2019: Glycolysis is an intrinsic factor for optimal replication of a norovirus[J]. MBio, , -.
-
Pelicano H, Martin DS, Xu RH, Huang P, 2006: Glycolysis inhibition for anticancer treatment[J]. Oncogene, 25, 4633-4646. doi: 10.1038/sj.onc.1209597
-
Petiot E, Jacob D, Lanthier S, Lohr V, Ansorge S, Kamen AA, 2011: Metabolic and kinetic analyses of influenza production in perfusion HEK293 cell culture[J]. BMC Biotechnol, 11, 84-. doi: 10.1186/1472-6750-11-84
-
Ren L, Zhang W, Han P, Zhang J, Zhu Y, Meng X, Zhang J, Hu Y, Yi Z, Wang R, 2019: Influenza A virus (H1N1) triggers a hypoxic response by stabilizing hypoxia-inducible factor-1alpha via inhibition of proteasome[J]. Virology, 530, 51-58. doi: 10.1016/j.virol.2019.02.010
-
Ritter JB, Wahl AS, Freund S, Genzel Y, Reichl U, 2010: Metabolic effects of influenza virus infection in cultured animal cells: intra-and extracellular metabolite profiling[J]. BMC Syst Biol, 4, 61-. doi: 10.1186/1752-0509-4-61
-
Sanchez EL, Lagunoff M, 2015: Viral activation of cellular metabolism[J]. Virology, 480, 479-480.
-
Schmittgen TD, Livak KJ, 2008: Analyzing real-time PCR data by the comparative C(T) method[J]. Nat Protoc, 3, 1101-1108. doi: 10.1038/nprot.2008.73
-
Semenza GL, 2012: Hypoxia-inducible factors in physiology and medicine[J]. Cell, 148, 399-408. doi: 10.1016/j.cell.2012.01.021
-
Smallwood HS, Duan S, Morfouace M, Rezinciuc S, Shulkin BL, Shelat A, Zink EE, Milasta S, Bajracharya R, Oluwaseum AJ, Roussel MF, Green DR, Pasa-Tolic L, Thomas PG, 2017: Targeting metabolic reprogramming by influenza infection for therapeutic intervention[J]. Cell Rep, 19, 1640-1653. doi: 10.1016/j.celrep.2017.04.039
-
Thai M, Graham NA, Braas D, Nehil M, Komisopoulou E, Kurdistani SK, McCormick F, Graeber TG, Christofk HR, 2014: Adenovirus E4ORF1-induced MYC activation promotes host cell anabolic glucose metabolism and virus replication[J]. Cell Metab, 19, 694-701. doi: 10.1016/j.cmet.2014.03.009
-
Thai M, Thaker SK, Feng J, Du Y, Hu H, Ting WuT, Graeber TG, Braas D, Christofk HR, 2015: MYC-induced reprogramming of glutamine catabolism supports optimal virus replication[J]. Nat Commun, 6, 8873-. doi: 10.1038/ncomms9873
-
Varanasi SK, Rouse BT, 2018: How host metabolism impacts on virus pathogenesis[J]. Curr Opin Virol, 28, 37-42. doi: 10.1016/j.coviro.2017.11.003
-
Wang GL, Semenza GL, 1993: General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia[J]. Proc Natl Acad Sci U S A, 90, 4304-4308. doi: 10.1073/pnas.90.9.4304
-
Wang GL, Semenza GL, 1995: Purification and characterization of hypoxia-inducible factor 1[J]. J Biol Chem, 270, 1230-1237. doi: 10.1074/jbc.270.3.1230
-
Wolf A, Agnihotri S, Micallef J, Mukherjee J, Sabha N, Cairns R, Hawkins C, Guha A, 2011: Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme[J]. J Exp Med, 208, 313-326. doi: 10.1084/jem.20101470
-
Xu C, Liu X, Zha H, Fan S, Zhang D, Li S, Xiao W, 2018: A pathogen-derived effector modulates host glucose metabolism by arginine GlcNAcylation of HIF-1alpha protein[J]. PLoS Pathog, 14, e1007259-. doi: 10.1371/journal.ppat.1007259
-
Yogev O, Lagos D, Enver T, Boshoff C, 2014: Kaposi's sarcoma herpesvirus microRNAs induce metabolic transformation of infected cells[J]. PLoS Pathog, 10, e1004400-. doi: 10.1371/journal.ppat.1004400
-
Yu Y, Maguire TG, Alwine JC, 2014: ChREBP, a glucose-responsive transcriptional factor, enhances glucose metabolism to support biosynthesis in human cytomegalovirus-infected cells[J]. Proc Natl Acad Sci U S A, 111, 1951-1956. doi: 10.1073/pnas.1310779111
-
Zhang W, Wang G, Xu ZG, Tu H, Hu F, Dai J, Chang Y, Chen Y, Lu Y, Zeng H, Cai Z, Han F, Xu C, Jin G, Sun L, Pan BS, Lai SW, Hsu CC, Xu J, Chen ZZ, Li HY, Seth P, Hu J, Zhang X, Li H, Lin HK, 2019: Lactate Is a natural suppressor of RLR signaling by targeting MAVS[J]. Cell, 178, 176-189. doi: 10.1016/j.cell.2019.05.003
-
Zhao Y, Chahar HS, Komaravelli N, Dossumekova A, Casola A, 2019: Human metapneumovirus infection of airway epithelial cells is associated with changes in core metabolic pathways[J]. Virology, 531, 183-191. doi: 10.1016/j.virol.2019.03.011
-
Zhao Y, Wang A, Zou Y, Su N, Loscalzo J, Yang Y, 2016: In vivo monitoring of cellular energy metabolism using SoNar, a highly responsive sensor for NAD(+)/NADH redox state[J]. Nat Protoc, 11, 1345-1359. doi: 10.1038/nprot.2016.074
-
Zumla A, Rao M, Wallis RS, Kaufmann SHE, Rustomjee R, Mwaba P, Vilaplana C, Yeboah-Manu D, Chakaya J, Ippolito G, Azhar E, Hoelscher M, Maeurer M, 2016: Host-directed therapies for infectious diseases: current status, recent progress, and future prospects[J]. Lancet Infect Dis, 16, e47-e63. doi: 10.1016/S1473-3099(16)00078-5