Figure 0个  Table 1个
    •     GF Mild Infection
      N = 128 for HLA-A and HLA-AB
      N = 128 for HLA-DRB1      		 GF Dead/ICU
      N = 48 HLA-A and HLA-AB
      N = 48 for HLA-DRB1      		 GF Normal
      N = 18774 HLA-A and HLA-AB
      N = 250 for HLA-DRB1
      HLA-A 01 0.016 0.010 0.008
      02 0.333 0.339 0.316
      03 0.012 0.010 0.011
      11 0.304 0.339 0.338
      24 0.161 0.134 0.145
      26 0.012 0.010 0.020
      29 0.004 0 0.012
      30 0.012 0.043 0.016
      31 0.020 0.010 0.015
      33 0.112 0.076 0.099
      34 0.004 0 0.001
      HLA-B 07 0.008 0 0.015
      13 0.091 0.149 0.092
      15 0.163 0.137 0.167
      18 0.004 0.011 0.004
      27 0.024 0.032 0.021
      35 0.024 0.011 0.032
      37 0.012 0.011 0.005
      38 0.048 0.043 0.051
      39 0.016 0.022 0.014
      60 0.163 0.149 0.149
      61 0.028 0.032 0.027
      44 0.020 0.011 0.014
      46 0.177 0.162 0.147
      48 0.012 0.032 0.017
      50 0.008 0 0.003
      51 0.053 0.022 0.047
      52 0.004 0.011 0.006
      54 0.032 0.066 0.021
      55 0.016 0 0.021
      56 0.004 0.022 0.009
      58 0.078 0.055 0.067
      67 0.008 0.011 0.002
      81 0.004 0 0
      HLA-DRB1 03 0.056 0.022 0.088
      04 0.129 0.113 0.100
      07 0.044 0.055 0.053
      08 0.060 0.055 0.045
      09 0.161 0.188 0.159
      10 0.016 0.032 0.022
      11 0.052 0.089 0.047
      12 0.176 0.201 0.176
      13 0.032 0.011 0.026
      14 0.069 0.066 0.075
      15 0.157 0.089 0.126
      16 0.056 0.077 0.062
      HLA-DRB1 gene frequencies (GF) were calculated by direct counting of observed alleles. For HLA-A and -B phenotype frequencies were first determined by direct counting and the method of Ceppellini (Ceppellini R et al., 1955) was used to calculate GF. Differences in allele number observed between cases and controls were evaluated using Fisher's exact test. P values were corrected for the number of observations made. No significant differences were observed.

      Table 1.  HLA gene frequencies (GF) in SARS patients and healthy controls