-
Almazán F, González JM, Pénzes Z, Izeta A, Calvo E, Plana-Durán J, Enjuanes L, 2000: Engineering the largest RNA virus genome as an infectious bacterial artificial chromosome[J]. Proc Natl Acad Sci USA, 97, 5516-5521. doi: 10.1073/pnas.97.10.5516
-
Almazán F, Sola I, Zuñiga S, Marquez-Jurado S, Morales L, Becares M, Enjuanes L, 2014: Coronavirus reverse genetic systems: infectious clones and replicons[J]. Virus Res, 189, 262-270. doi: 10.1016/j.virusres.2014.05.026
-
Bartenschlager R, Kaul A, Sparacio S, 2003: Replication of the hepatitis C virus in cell culture[J]. Antivir Res, 60, 91-102. doi: 10.1016/j.antiviral.2003.08.016
-
Choy KT, Wong AY, Kaewpreedee P, Sia SF, Chen D, Hui K, Chu D, Chan M, Cheung PP, Huang X, Peiris M, Yen HL, 2020: Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro[J]. Antivir Res, 178, 104786-. doi: 10.1016/j.antiviral.2020.104786
-
de Wit E, Feldmann F, Cronin J, Jordan R, Okumura A, Thomas T, Scott D, Cihlar T, Feldmann H, 2020: Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection[J]. Proc Natl Acad Sci USA, 117, 6771-6776. doi: 10.1073/pnas.1922083117
-
Drosten C, Günther S, Preiser W, van der Werf S, Brodt HR, Becker S, Rabenau H, Panning M, Kolesnikova L, Fouchier RA, Berger A, Burguière AM, 2003: Identification of a novel coronavirus in patients with severe acute respiratory syndrome[J]. N Engl J Med, 348, 1967-1976. doi: 10.1056/NEJMoa030747
-
Ge F, Luo Y, Liew PX, Hung E, 2007: Derivation of a novel SARS-coronavirus replicon cell line and its application for anti-SARS drug screening[J]. Virology, 360, 150-158. doi: 10.1016/j.virol.2006.10.016
-
Hashemian SM, Farhadi T, Velayati AA, 2020: A review on remdesivir: a possible promising agent for the treatment of COVID-19[J]. Drug Des Dev Ther, 14, 3215-3222. doi: 10.2147/DDDT.S261154
-
Horscroft N, Lai VC, Cheney W, Yao N, Wu JZ, Hong Z, Zhong W, 2005: Replicon cell culture system as a valuable tool in antiviral drug discovery against hepatitis C virus[J]. Antivir Chem Chemother, 16, 1-12. doi: 10.1177/095632020501600101
-
Hou YJ, Okuda K, Edwards CE, Martinez DR, Asakura T, Dinnon KR, Kato T, Lee RE, Yount BL, Mascenik TM, Chen G, Olivier KN, Ghio A, Tse LV, Leist SR, Gralinski LE, Schäfer A, Dang H, Gilmore R, Nakano S, Sun L, Fulcher ML, Livraghi-Butrico A, Nicely NI, Cameron M, Cameron C, Kelvin DJ, de Silva A, Margolis DM, Markmann A, Bartelt L, Zumwalt R, Martinez FJ, Salvatore SP, Borczuk A, Tata PR, Sontake V, Kimple A, Jaspers I, OoNeal WK, Randell SH, Boucher RC, Baric RS, 2020: SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract[J]. Cell, 182, 429-446. doi: 10.1016/j.cell.2020.05.042
-
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, Zhang L, Fan G, Xu J, Gu X, Cheng Z, Yu T, Xia J, Wei Y, Wu W, Xie X, Yin W, Li H, Liu M, Xiao Y, Gao H, Guo L, Xie J, Wang G, Jiang R, Gao Z, Jin Q, Wang J, Cao B, 2020: Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China[J]. Lancet, 395, 497-506. doi: 10.1016/S0140-6736(20)30183-5
-
Kim JC, Spence RA, Currier PF, Lu X, Denison MR, 1995: Coronavirus protein processing and RNA synthesis is inhibited by the cysteine proteinase inhibitor E64d[J]. Virology, 208, 1-8. doi: 10.1006/viro.1995.1123
-
Kotaki T, Xie X, Shi P, Kameoka M (2020) A PCR amplicon-based SARS-CoV-2 replicon for antiviral screening. bioRxiv.
-
Nikiforuk AM, Leung A, Cook B, Court DA, Kobasa D, Theriault SS, 2016: Rapid one-step construction of a Middle East Respiratory Syndrome (MERS-CoV) infectious clone system by homologous recombination[J]. J Virol Methods, 236, 178-183. doi: 10.1016/j.jviromet.2016.07.022
-
Pruijssers AJ, George AS, Schäfer A, Leist SR, Gralinksi LE, Dinnon KR, Yount BL, Agostini ML, Stevens LJ, Chappell JD, Lu X, Hughes TM, Gully K, Martinez DR, Brown AJ, Graham RL, Perry JK, Du Pont V, Pitts J, Ma B, Babusis D, Murakami E, Feng JY, Bilello JP, Porter DP, Cihlar T, Baric RS, Denison MR, Sheahan TP, 2020: Remdesivir inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice[J]. Cell Rep, 32, 107940-. doi: 10.1016/j.celrep.2020.107940
-
Ren LL, Wang YM, Wu ZQ, Xiang ZC, Guo L, Xu T, Jiang YZ, Xiong Y, Li YJ, Li XW, Li H, Fan GH, Gu XY, Xiao Y, Gao H, Xu JY, Yang F, Wang XM, Wu C, Chen L, Liu YW, Liu B, Yang J, Wang XR, Dong J, Li L, Huang CL, Zhao JP, Hu Y, Cheng ZS, Liu LL, Qian ZH, Qin C, Jin Q, Cao B, Wang JW, 2020: Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study[J]. Chin Med J (Engl), 133, 1015-1024. doi: 10.1097/CM9.0000000000000722
-
Sheahan TP, Sims AC, Graham RL, Menachery VD, Gralinski LE, Case JB, Leist SR, Pyrc K, Feng JY, Trantcheva I, Bannister R, Park Y, Babusis D, Clarke MO, Mackman RL, Spahn JE, Palmiotti CA, Siegel D, Ray AS, Cihlar T, Jordan R, Denison MR, Baric RS (2017) Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses. Sci Transl Med 9: aal3653
-
Shi M, Wang L, Fontana P, Vora S, Zhang Y, Fu TM, Lieberman J, Wu H (2020) SARS-CoV-2 Nsp1 suppresseshost but not viral translation through a bipartite mechanism. bioRxiv.
-
Thi NTT, Labroussaa F, Ebert N, VoKovski P, Stalder H, Portmann J, Kelly J, Steiner S, Holwerda M, Kratzel A, Gultom M, Schmied K, Laloli L, Hüsser L, Wider M, Pfaender S, Hirt D, Cippà V, Crespo-Pomar S, Schröder S, Muth D, Niemeyer D, Corman VM, Müller MA, Drosten C, Dijkman R, Jores J, Thiel V, 2020: Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform[J]. Nature, 582, 561-565. doi: 10.1038/s41586-020-2294-9
-
Thiel V, Siddell SG, 2005: Reverse genetics of coronaviruses using vaccinia virus vectors[J]. Curr Top Microbiol Immunol, 287, 199-227.
-
Wang JM, Wang LF, Shi ZL, 2008: Construction of a non-infectious SARS coronavirus replicon for application in drug screening and analysis of viral protein function[J]. Biochem Biophys Res Commun, 374, 138-142. doi: 10.1016/j.bbrc.2008.06.129
-
Wang M, Cao R, Zhang L, Yang X, Liu J, Xu M, Shi Z, Hu Z, Zhong W, Xiao G, 2020: Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro[J]. Cell Res, 30, 269-271. doi: 10.1038/s41422-020-0282-0
-
Xia H, Cao Z, Xie X, Zhang X, Chen JY, Wang H, Menachery VD, Rajsbaum R, Shi PY, 2020: Evasion of type I interferon by SARS-CoV-2[J]. Cell Rep, 33, 108234-. doi: 10.1016/j.celrep.2020.108234
-
Xie X, Muruato A, Lokugamage KG, Narayanan K, Zhang X, Zou J, Liu J, Schindewolf C, Bopp NE, Aguilar PV, Plante KS, Weaver SC, Makino S, LeDuc JW, Menachery VD, Shi PY, 2020: An infectious cDNA clone of SARS-CoV-2[J]. Cell Host Microbe, 27, 841-848. doi: 10.1016/j.chom.2020.04.004
-
Yount B, Curtis KM, Baric RS, 2000: Strategy for systematic assembly of large RNA and DNA genomes: transmissible gastroenteritis virus model[J]. J Virol, 74, 10600-10611. doi: 10.1128/JVI.74.22.10600-10611.2000
-
Yount B, Curtis KM, Fritz EA, Hensley LE, Jahrling PB, Prentice E, Denison MR, Geisbert TW, Baric RS, 2003: Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus[J]. Proc Natl Acad Sci USA, 100, 12995-13000. doi: 10.1073/pnas.1735582100
-
Yuan S, Peng L, Park JJ, Hu Y, Devarkar SC, Dong MB, Shen Q, Wu S, Chen S, Lomakin IB, Xiong Y, 2020: Nonstructural protein 1 of SARS-CoV-2 is a potent pathogenicity factor redirecting host protein synthesis machinery toward viral RNA[J]. Mol Cell, 80, 1055-1066. doi: 10.1016/j.molcel.2020.10.034
-
Zaki AM, van Boheemen S, Bestebroer TM, Osterhaus AD, Fouchier RA, 2012: Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia[J]. N Engl J Med, 367, 1814-1820. doi: 10.1056/NEJMoa1211721
-
Zhang Y, Song W, Chen S, Yuan Z, Yi Z, 2020: A bacterial artificial chromosome (BAC)-vectored noninfectious replicon of SARS-CoV-2[J]. Antivir Res, 185, 104974-.
-
Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W, Si HR, Zhu Y, Li B, Huang CL, Chen HD, Chen J, Luo Y, Guo H, Jiang RD, Liu MQ, Chen Y, Shen XR, Wang X, Zheng XS, Zhao K, Chen QJ, Deng F, Liu LL, Yan B, Zhan FX, Wang YY, Xiao GF, Shi ZL, 2020: A pneumonia outbreak associated with a new coronavirus of probable bat origin[J]. Nature, 579, 270-273. doi: 10.1038/s41586-020-2012-7