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Genome region Nucleotide changes Amino acid changes Polyprotein numbering Mature protein numbering VP4 (747-953) A 809 G E 21 G E 21 G VP2 (954-1715) G 1359 A V 204 I V 135 I G 1385 C S 213 T S 144 T A 1400 T K 218 I K 149 I G 1429 C E 228 P E 159 P A 1430 C E 228 P E 159 P VP3 (1716-2441) G 1900 C A 385 P A 62 P A 2287 G T 514A T 191 A A 2413 T S 556 C S 233C A 2421 G I 558 M I 235 M VP1 (2442-3332) T 2462 C V 572 A V 7 A C 2530 A Q 595 K Q 30 K A 2719 G I 658 V I 93 V T 2724 A D 659 E D 94 E A 2734 G K 663 E K 98 E A 2753 G N 669 G N 104 G A 2876 C E 710 A E 145 A A 2943 T E 732 D E 167 D C 2947 T L 734 F L 169 F C 3165 T S 806 L S 241 L T 3175 C Y 810 H Y 245 H A 3286 G N 847 D N 282 D G 3319 T A 858 S A 293 S Amino acid substitutions that fall within the VP1 canyon surrounding Gln-172 are given in italics. Table 1. Non-synonymous mutations in the capsid region (P1) EV71:TLLcho relative to EV71:BS.
Figure 2 个
Table 1 个