• Ahishali, B., Kaya, M., 2021. Evaluation of Blood-Brain Barrier Integrity Using Vascular Permeability Markers: Evans Blue, Sodium Fluorescein, Albumin-Alexa Fluor Conjugates, and Horseradish Peroxidase. Methods Mol Biol, 236787-103.

  • Alam, A., Sudarwati, S., Hakim, D., Mahdiani, S., 2021. Case Report: Severe COVID-19 and Dengue in an Indonesian Infant. Am J Trop Med Hyg 104, 1456-1460.

  • Albert-Weissenberger, C., Mencl, S., Schuhmann, M. K., Salur, I., Gob, E., Langhauser, F., Hopp, S., Hennig, N., Meuth, S. G., Nolte, M. W., Siren, A., Kleinschnitz, C., 2014. C1-Inhibitor protects from focal brain trauma in a cortical cryolesion mice model by reducing thrombo-inflammation. Front Cell Neurosci, 8, 269.

  • Anshad, A. R., Saravanan, S., Murugesan, A., Vighnesh, R., Raju, S., Kannan, R., Yong, Y. K., Larsson, M., Shankar, E. M., 2026. Aberrant systemic acute-phase complement responses in conjunction with soluble CR1 attribute to varying grades of dengue disease severity. Front Immunol, 16:1731011.

  • Avirutnan, P., Hauhart, R. E., Marovich, M. A., Garred, P., Atkinson, J. P., Diamond, M. S., 2011. Complement-mediated neutralization of dengue virus requires mannose-binding lectin, mBio, 2, e00276-11.

  • Avirutnan, P., Malasit, P., Seliger, B., Bhakdi, S., Husmann, M. 1998. Dengue virus infection of human endothelial cells leads to chemokine production, complement activation, and apoptosis. J Immunol, 161, 6338-6346.

  • Avirutnan, P., Punyadee, N., Noisakran, S., Komoltri, C., Thiemmeca, S., Auethavornanan, K., Jairungsri, A., Kanlaya, R., Tangthawornchaikul, N., Puttikhunt, C., Pattanakitsakul, S., Yenchitsomanus, P., Mongkolsapaya, J., Kasinrerk, W., Sittisombut, N., Husmann, M., Blettner, M., Vasanawathana, S., Bhakdi, S., Malasit, P., 2006. Vascular leakage in severe dengue virus infections: a potential role for the nonstructural viral protein NS1 and complement. The Journal of infectious diseases, 193, 1078-1088.

  • Avirutnan, P., Zhang, L., Punyadee, N., Manuyakorn, A., Puttikhunt, C., Kasinrerk, W., Malasit, P., Atkinson, J. P., Diamond, M. S., 2007. Secreted NS1 of dengue virus attaches to the surface of cells via interactions with heparan sulfate and chondroitin sulfate E. PLoS Pathog, 3, e183.

  • Bhatt, S., Gething, P. W., Brady, O. J., Messina, J. P., Farlow, A. W., Moyes, C. L., Drake, J. M., Brownstein, J. S., Hoen, A. G., Sankoh, O., Myers, M. F., George, D. B., Jaenisch, T., Wint, G. R., Simmons, C. P., Scott, T. W., Farrar, J. J., Hay, S. I., 2013. The global distribution and burden of dengue. Nature, 496, 504-507.

  • Bruck, W., Bruck, Y., Diederich, U., Piddlesden, S. J. 1995. The membrane attack complex of complement mediates peripheral nervous system demyelination in vitro. Acta Neuropathol, 90, 601-607.

  • Brunner, J., Prelog, M., Riedl, M., Giner, T., Hofer, J., Wurzner, R., Zimmerhackl, L. B., 2012. Analysis of the classical, alternative, and mannose binding lectin pathway of the complement system in the pathogenesis of oligoarticular juvenile idiopathic arthritis, Rheumatol Int, 32, 1815-1818.

  • Byrne, A. B., Bonnin, F. A., Lopez, E. L., Polack, F. P., Talarico, L. B., 2024. C1q modulation of antibody-dependent enhancement of dengue virus infection in human myeloid cell lines is dependent on cell type and antibody specificity. Microbes and infection, 26, 105378.

  • Byrne, A. B., Talarico, L. B. 2021. Role of the complement system in antibody-dependent enhancement of flavivirus infections. Int J Infect Dis, 103, 404-411.

  • Cabezas, S., Bracho, G., Aloia, A. L., Adamson, P. J., Bonder, C. S., Smith, J. R., Gordon, D. L., Carr, J. M., 2018. Dengue Virus Induces Increased Activity of the Complement Alternative Pathway in Infected Cells, Journal of virology, 92, e00633-18.

  • Cabezas-Falcon, S., Norbury, A. J., Hulme-Jones, J., Klebe, S., Adamson, P., Rudd, P. A., Mahalingam, S., Ong, L., Alonso, S., Gordon, D. L., Carr, J. M., 2021. Changes in complement alternative pathway components, factor B and factor H during dengue virus infection in the AG129 mouse, J Gen Virol. 102, 001547.

  • Cao, J., Spielmann, M., Qiu, X., Huang, X., Ibrahim, D. M., Hill, A. J., Zhang, F., Mundlos, S., Christiansen, L., Steemers, F. J., Trapnell, C., Shendure, J. 2019. The single-cell transcriptional landscape of mammalian organogenesis, Nature, 566, 496-502.

  • Carr, J. M., Cabezas-Falcon, S., Dubowsky, J. G., Hulme-Jones, J., Gordon, D. L. 2020. Dengue virus and the complement alternative pathway, FEBS letters, 594, 2543-2555.

  • Chen, C., Chan, K., Yu, W., Cheng, K., Chao, H., Yeh, C., Lai, C. 2016. The outcomes of patients with severe dengue admitted to intensive care units, Medicine, 95, e4376.

  • Q., Chen, W, Yang, Y.Z., Yuan, F.Z., Cai, W.J., Peng, Z., Li, D, Li, J.F., Liu, J.T., Yang, W., Wang, Disruption of carbon metabolism by the hepatic mononuclear phagocytic system drives liver injury in a mouse model of severe dengue, J. Hepatol., 2026, S0168-8278(26)02737-6.

  • Chen, Q., Yuan, Y., Cai, F., Li, Z., Wei, Q., Wang, W., 2024. Single-Nucleus and Spatial Transcriptomics Revealing Host Response Differences Triggered by Mutated Virus in Severe Dengue, Viruses, 16, 1779.

  • Conde, J. N., Da Silva, E. M., Allonso, D., Coelho, D. R., Andrade, I. D. S., De Medeiros, L. N., Menezes, J. L., Barbosa, A. S., Mohana-Borges, R., 2016. Inhibition of the Membrane Attack Complex by Dengue Virus NS1 through Interaction with Vitronectin and Terminal Complement Proteins, Journal of virology, 90, 9570-9581.

  • Conde, J. N., Silva, E. M., Barbosa, A. S., Mohana-Borges, R. 2017. The Complement System in Flavivirus Infections, Front Microbiol, 8, 213.

  • Cui, L., Pang, J., Lee, Y. H., Ooi, E. E., Ong, C. N., Leo, Y. S., Tannenbaum, S. R. 2018. Serum metabolome changes in adult patients with severe dengue in the critical and recovery phases of dengue infection, PLoS Negl Trop Dis, 12, e0006217.

  • Da, S. N., Undurraga, E. A., Da, S. F. E., Estofolete, C. F., Nogueira, M. L. 2018. Clinical, laboratory, and demographic determinants of hospitalization due to dengue in 7613 patients: A retrospective study based on hierarchical models, Acta Trop, 177, 25-31.

  • Davis, A. E. R. 2004. Biological effects of C1 inhibitor, Drug news & perspectives, 17, 439-446.

  • Davis, A. E. R., Mejia, P., Lu, F., 2008. Biological activities of C1 inhibitor, Molecular immunology, 45, 4057-4063.

  • Davis, J. S., Bourke, P. 2004. Rhabdomyolysis associated with dengue virus infection, Clin Infect Dis, 38, e109-e111.

  • Dejnirattisai, W., Jumnainsong, A., Onsirisakul, N., Fitton, P., Vasanawathana, S., Limpitikul, W., Puttikhunt, C., Edwards, C., Duangchinda, T., Supasa, S., Chawansuntati, K., Malasit, P., Mongkolsapaya, J., Screaton, G. 2010. Cross-reacting antibodies enhance dengue virus infection in humans, Science, 328, 745-748.

  • Diep, N. T., Giang, N. T., Diu, N. T. T., Nam, N. M., Khanh, L. V., Quang, H. V., Hang, N. T., Mao, C. V., Son, H. V., Hieu, N. L., Linh, P. T., Sklan, E. H., Toan, N. L., Tong, H. V., 2023. Complement receptor type 1 and 2 (CR1 and CR2) gene polymorphisms and plasma protein levels are associated with the Dengue disease severity, Scientific reports, 13, 17377.

  • Dodds, A. W. 2002. Which came first, the lectin/classical pathway or the alternative pathway of complement?, Immunobiology, 205, 340-354.

  • Dos, S. B., Gandolfi, F. A., Milhim, B., Dourado, F. S., Silva, G., Zini, N., Gratao, V., Mariani, M. P., Abbas, T. N., Garcia, P., Rocha, R. S., Vasilakis, N., Nogueira, M. L., Estofolete, C. F, 2024. Diabetes as risk factor to severity of dengue in naive patients, medRxiv, doi: 10.1101/2024.04.27.24306485.

  • Douradinha, B., Mcburney, S. P., Soares, D. M. K., Smith, A. P., Krishna, N. K., Barratt-Boyes, S. M., Evans, J. D., Nascimento, E. J., Marques, E. J, 2014. C1q binding to dengue virus decreases levels of infection and inflammatory molecules transcription in THP-1 cells, Virus Res, 179, 231-234.

  • Dunkelberger, J. R., Song, W. C, 2010. Complement and its role in innate and adaptive immune responses, Cell Res, 20, 34-50.

  • Fuchs, A., Lin, T., Beasley, D. W., Stover, C. M., Schwaeble, W. J., Pierson, T. C., Diamond, M. S, 2010. Direct complement restriction of flavivirus infection requires glycan recognition by mannose-binding lectin, Cell Host, Microbe, 8, 186-195.

  • Gasque, P., Dean, Y. D., Mcgreal, E. P., Vanbeek, J., Morgan, B. P, 2000. Complement components of the innate immune system in health and disease in the CNS, Immunopharmacology, 49, 171-186.

  • Ghebrehiwet, B., Hosszu, K. H., Peerschke, E. I. B, 2017. C1q as an autocrine and paracrine regulator of cellular functions", Molecular immunology, 8426-8433.

  • Ghita, L., Yao, Z., Xie, Y., Duran, V., Cagirici, H. B., Samir, J., Osman, I., Rebellon-Sanchez, D. E., Agudelo-Rojas, O. L., Sanz, A. M., Sahoo, M. K., Robinson, M. L., Gelvez-Ramirez, R. M., Bueno, N., Luciani, F., Pinsky, B. A., Montoya, J. G., Estupinan-Cardenas, M. I., Villar-Centeno, L. A., Rojas-Garrido, E. M., Rosso, F., Quake, S. R., Zanini, F., Einav, S, 2023. Global and cell type-specific immunological hallmarks of severe dengue progression identified via a systems immunology approach, Nat Immunol, 24, 2150-2163.

  • Giang, N. T., Van Tong, H., Quyet, D., Hoan, N. X., Nghia, T. H., Nam, N. M., Hung, H. V., Anh, D. T., Van Mao, C., Son, H. A., Meyer, C. G., Velavan, T. P., Toan, N. L, 2020. Complement protein levels and MBL2 polymorphisms are associated with dengue and disease severity, Scientific reports, 10, 14923.

  • Halstead, S. B, 1989. Antibody, macrophages, dengue virus infection, shock, and hemorrhage: a pathogenetic cascade", Rev Infect Dis, 11 Suppl 4S830-9.

  • Halstead, S. B, 2007. "Dengue", Lancet, 370, 1644-1652.

  • Halstead, S. B., O'rourke, E. J, 1977. Dengue viruses and mononuclear phagocytes. I. Infection enhancement by non-neutralizing antibody, J Exp Med, 146, 201-217.

  • Hassan, J., Borhany, M., Abid, M., Zaidi, U., Fatima, N., Shamsi, T, 2020. Coagulation abnormalities in dengue and dengue haemorrhagic fever patients, Transfus Med, 30, 46-50.

  • He, S., Fan, D., Guo, Y., Guan, Y., Sheng, Z., Gao, N., An, J., 2026. Current status of dengue fever epidemics and vaccine development. Virol Sin, 41, 1-9.

  • Iqtadar, S., Akbar, N., Mehmood, M., Abaidullah, S, 2017. Clinical Audit of Dengue Related Deaths in 2011-Mayo Hospital Lahore Pakistan, Pak J Med Sci, 33, 1070-1073.

  • Jin, S., Guerrero-Juarez, C. F., Zhang, L., Chang, I., Ramos, R., Kuan, C. H., Myung, P., Plikus, M. V., Nie, Q, 2021. "Inference and analysis of cell-cell communication using CellChat", Nat Commun, 12, 1088.

  • John, D. V., Lin, Y., Perng, G. C, 2015. Biomarkers of severe dengue disease - a review, Journal of biomedical science, 22, 83.

  • Kakogiannos, N., Ferrari, L., Giampietro, C., Scalise, A. A., Maderna, C., Rava, M., Taddei, A., Lampugnani, M. G., Pisati, F., Malinverno, M., Martini, E., Costa, I., Lupia, M., Cavallaro, U., Beznoussenko, G. V., Mironov, A. A., Fernandes, B., Rudini, N., Dejana, E., Giannotta, M, 2020. JAM-A Acts via C/EBP-alpha to Promote Claudin-5 Expression and Enhance Endothelial Barrier Function", Circ Res, 127, 1056-1073.

  • Kosuru, R., Romito, O., Sharma, G. P., Ferraresso, F., Ghadrdoost, N. B., Yang, K., Mammoto, T., Mammoto, A., Kastrup, C. J., Zhang, D. X., Goldspink, P. H., Trebak, M., Chrzanowska, M, 2024. Rap1A Modulates Store-Operated Calcium Entry in the Lung Endothelium: A Novel Mechanism Controlling NFAT-Mediated Vascular Inflammation and Permeability, Arterioscler Thromb Vasc Biol, 44, 2271-2287.

  • Kraivong, R., Punyadee, N., Liszewski, M. K., Atkinson, J. P., Avirutnan, P, 2021. Dengue and the Lectin Pathway of the Complement System, Viruses, 13, 1219.

  • Kyle, J. L., Balsitis, S. J., Zhang, L., Beatty, P. R., Harris, E, 2008. Antibodies play a greater role than immune cells in heterologous protection against secondary dengue virus infection in a mouse model, Virology, 380, 296-303.

  • Liu, D., Zhang, D., Scafidi, J., Wu, X., Cramer, C. C., Davis, A. E. R, 2005. C1 inhibitor prevents Gram-negative bacterial lipopolysaccharide-induced vascular permeability, Blood, 105, 2350-2355.

  • Loos, M, 1982. The classical complement pathway: mechanism of activation of the first component by antigen-antibody complexes, Prog Allergy, 30, 135-192.

  • Lu, F., Fernandes, S. M., Davis, A. E. R, 2010. The role of the complement and contact systems in the dextran sulfate sodium-induced colitis model: the effect of C1 inhibitor in inflammatory bowel disease, American journal of physiology. Gastrointestinal and liver physiology, 298, G878-G883.

  • Lu, J., Kishore, U, 2017. C1 Complex: An Adaptable Proteolytic Module for Complement and Non-Complement Functions, Frontiers in immunology, 8, 592.

  • Lu, J., Wu, X., Teh, B. K, 2007. The regulatory roles of C1q, Immunobiology, 212, 245-252.

  • Maere, S., Heymans, K., Kuiper, M, 2005. BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks, Bioinformatics, 21, 3448-3449.

  • Malavige, G. N., Ogg, G. S, 2017. Pathogenesis of vascular leak in dengue virus infection, Immunology, 151, 261-269.

  • Malavige, G. N., Ogg, G. S, 2024. Molecular mechanisms in the pathogenesis of dengue infections, Trends in molecular medicine, 30, 484-498.

  • Maloney, B. E., Perera, K. D., Saunders, D. R. D., Shadipeni, N., Fleming, S. D, 2020. Interactions of viruses and the humoral innate immune response, Clinical immunology, 212, 108351.

  • Marinho, C. F., Azeredo, E. L., Torrentes-Carvalho, A., Marins-Dos-Santos, A., Kubelka, C. F., De Souza, L. J., Cunha, R. V., De-Oliveira-Pinto, L. M, 2014. Down-regulation of complement receptors on the surface of host monocyte even as in vitro complement pathway blocking interferes in dengue infection, PloS one, 9, e102014.

  • Mehlhop, E., Ansarah-Sobrinho, C., Johnson, S., Engle, M., Fremont, D. H., Pierson, T. C., Diamond, M. S, 2007. Complement protein C1q inhibits antibody-dependent enhancement of flavivirus infection in an IgG subclass-specific manner, Cell host, microbe, 2, 417-426.

  • Messina, J. P., Brady, O. J., Golding, N., Kraemer, M., Wint, G., Ray, S. E., Pigott, D. M., Shearer, F. M., Johnson, K., Earl, L., Marczak, L. B., Shirude, S., Davis, W. N., Gilbert, M., Velayudhan, R., Jones, P., Jaenisch, T., Scott, T. W., Reiner, R. J., Hay, S. I, 2019. The current and future global distribution and population at risk of dengue, Nat Microbiol, 4, 1508-1515.

  • Meuren, L. M., Prestes, E. B., Papa, M. P., De Carvalho, L., Mustafa, Y. M., Da, C. L., Da, P. A., Bozza, M. T., Arruda, L. B, 2022. Infection of Endothelial Cells by Dengue Virus Induces ROS Production by Different Sources Affecting Virus Replication, Cellular Activation, Death and Vascular Permeability, Front Immunol, 13, 810376.

  • Mortensen, S. A., Sander, B., Jensen, R. K., Pedersen, J. S., Golas, M. M., Jensenius, J. C., Hansen, A. G., Thiel, S., Andersen, G. R, 2017. Structure and activation of C1, the complex initiating the classical pathway of the complement cascade, Proceedings of the National Academy of Sciences of the United States of America, 114, 986-991.

  • Murugananthan, K., Coonghe, D., Kumanan, T., Murugananthan, A., Selvaratnam, G., Sivansuthan, S., Sathiadas, G., Ketheesan, N., A, C. F., Noordeen, F, 2023. Characteristics of the initial dengue outbreaks in a region without dengue prior to mid-2009 in a dengue-endemic country, J Infect Dev Ctries, 17, 260-267.

  • Nascimento, E. J., Silva, A. M., Cordeiro, M. T., Brito, C. A., Gil, L. H., Braga-Neto, U., Marques, E. T, 2009. Alternative complement pathway deregulation is correlated with dengue severity, PLoS One, 4, e6782.

  • Nascimento, E. J. M., Hottz, E. D., Garcia-Bates, T. M., Bozza, F., Marques, E. T. A. J., Barratt-Boyes, S. M, 2014. Emerging concepts in dengue pathogenesis: interplay between plasmablasts, platelets, and complement in triggering vasculopathy, Critical reviews in immunology, 34, 227-240.

  • Otasek, D., Morris, J. H., Boucas, J., Pico, A. R., Demchak, B, 2019. Cytoscape Automation: empowering workflow-based network analysis, Genome Biol, 20, 185.

  • Palarasah, Y., Nielsen, C., Sprogoe, U., Christensen, M. L., Lillevang, S., Madsen, H. O., Bygum, A., Koch, C., Skjodt, K., Skjoedt, M. O, 2011. Novel assays to assess the functional capacity of the classical, the alternative and the lectin pathways of the complement system, Clin Exp Immunol, 164, 388-395.

  • Pan, P., Li, G., Shen, M., Yu, Z., Ge, W., Lao, Z., Fan, Y., Chen, K., Ding, Z., Wang, W., Wan, P., Shereen, M. A., Luo, Z., Chen, X., Zhang, Q., Lin, L., Wu, J, 2021. DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction", PLoS Pathog, 17, e1008603.

  • Pan, P., Zhang, Q., Liu, W., Wang, W., Yu, Z., Lao, Z., Zhang, W., Shen, M., Wan, P., Xiao, F., Shereen, M. A., Zhang, W., Tan, Q., Liu, Y., Liu, X., Wu, K., Liu, Y., Li, G., Wu, J, 2019. Dengue Virus Infection Activates Interleukin-1β to Induce Tissue Injury and Vascular Leakage", Frontiers in microbiology, 10, 2637.

  • Porter, R. R., Reid, K. B, 1979. Activation of the complement system by antibody-antigen complexes: the classical pathway, Adv Protein Chem, 33, 1-71.

  • Pothapregada, S., Kamalakannan, B., Thulasingham, M., Sampath, S, 2016. Clinically Profiling Pediatric Patients with Dengue, J Glob Infect Dis, 8, 115-120.

  • Puerta-Guardo, H., Glasner, D. R., Harris, E, 2016. Dengue Virus NS1 Disrupts the Endothelial Glycocalyx, Leading to Hyperpermeability, PLoS Pathog, 12, e1005738.

  • Qiu, X., Mao, Q., Tang, Y., Wang, L., Chawla, R., Pliner, H. A., Trapnell, C, 2017. Reversed graph embedding resolves complex single-cell trajectories, Nat Methods, 14, 979-982.

  • Ramaglia, V., King, R. H., Nourallah, M., Wolterman, R., De Jonge, R., Ramkema, M., Vigar, M. A., Van Der Wetering, S., Morgan, B. P., Troost, D., Baas, F, 2007. The membrane attack complex of the complement system is essential for rapid Wallerian degeneration, J Neurosci, 27, 7663-7672.

  • Robinson, M. L., Glass, D. R., Duran, V., Agudelo, R. O., Sanz, A. M., Consuegra, M., Sahoo, M. K., Hartmann, F. J., Bosse, M., Gelvez, R. M., Bueno, N., Pinsky, B. A., Montoya, J. G., Maecker, H., Estupinan, C. M., Villar, C. L., Garrido, E., Rosso, F., Bendall, S. C., Einav, S, 2023. Magnitude and kinetics of the human immune cell response associated with severe dengue progression by single-cell proteomics, Sci Adv, 9, eade7702.

  • Rothman, A. L, 2010. Cellular immunology of sequential dengue virus infection and its role in disease pathogenesis, Curr Top Microbiol Immunol, 338, 83-98.

  • Saptarini, I., Masyeni, S., Harahap, A. R., Giantini, A., Nugroho, P., Handito, A., Hendarwan, H., Susilo, A., Haryanto, S., Fitriani, D., Sasmono, R. T., Nelwan, E. J, 2026. Dengue severity and profiles of complement activation and immune mediators: A multicenter cohort study in Indonesia, PloS One, 21, e0350610.

  • Sarathy, V. V., Milligan, G. N., Bourne, N., Barrett, A. D. T, 2015. Mouse models of dengue virus infection for vaccine testing, Vaccine, 33, 7051-7060.

  • Shresta, S, 2012. "Role of complement in dengue virus infection: protection or pathogenesis?, mBio, 3, e00003-12.

  • Silva, E. M., Conde, J. N., Allonso, D., Nogueira, M. L., Mohana-Borges, R, 2013. Mapping the interactions of dengue virus NS1 protein with human liver proteins using a yeast two-hybrid system: identification of C1q as an interacting partner, PLoS One, 8, e57514.

  • Sinnathamby, E. S., Issa, P. P., Roberts, L., Norwood, H., Malone, K., Vemulapalli, H., Ahmadzadeh, S., Cornett, E. M., Shekoohi, S., Kaye, A. D, 2023. Hereditary Angioedema: Diagnosis, Clinical Implications, and Pathophysiology, Adv Ther, 40, 814-827.

  • Srichaikul, T., Nimmanitaya, S., Artchararit, N., Siriasawakul, T., Sungpeuk, P, 1977. Fibrinogen metabolism and disseminated intravascular coagulation in dengue hemorrhagic fever, Am J Trop Med Hyg, 26, 525-532.

  • Stanaway, J. D., Shepard, D. S., Undurraga, E. A., Halasa, Y. A., Coffeng, L. E., Brady, O. J., Hay, S. I., Bedi, N., Bensenor, I. M., Castaneda-Orjuela, C. A., Chuang, T. W., Gibney, K. B., Memish, Z. A., Rafay, A., Ukwaja, K. N., Yonemoto, N., Murray, C, 2016. The global burden of dengue: an analysis from the Global Burden of Disease Study 2013, Lancet Infect Dis, 16, 712-723.

  • Sundler Bjorkman, L., Eswaran, H., Grover, S. P, 2026. Therapeutic Potential of C1-Inhibitor in Vascular Diseases and Beyond, Arteriosclerosis, thrombosis, and vascular biology, 46, e323743.

  • Suppiah, J., Md, S. S., Hassan, S. S., Nadzar, N., Ibrahim, N., Thayan, R., Mohd, Z. R, 2025. Unraveling potential gene biomarkers for dengue infection through RNA sequencing, Virus Genes, 61, 26-37.

  • The, Lancet, 2024. Dengue: the threat to health now and in the future, Lancet, 404, 311.

  • Thiemmeca, S., Tamdet, C., Punyadee, N., Prommool, T., Songjaeng, A., Noisakran, S., Puttikhunt, C., Atkinson, J. P., Diamond, M. S., Ponlawat, A., Avirutnan, P, 2016. Secreted NS1 Protects Dengue Virus from Mannose-Binding Lectin-Mediated Neutralization, J Immunol, 197, 4053-4065.

  • Thomas, S., Smatti, M. K., Ouhtit, A., Cyprian, F. S., Almaslamani, M. A., Thani, A. A., Yassine, H. M, 2022. Antibody-Dependent Enhancement (ADE) and the role of complement system in disease pathogenesis, Molecular immunology, 152, 172-182.

  • Tsai, W. Y., Durbin, A., Tsai, J. J., Hsieh, S. C., Whitehead, S., Wang, W. K, 2015. Complexity of Neutralizing Antibodies against Multiple Dengue Virus Serotypes after Heterotypic Immunization and Secondary Infection Revealed by In-Depth Analysis of Cross-Reactive Antibodies, J Virol, 89, 7348-7362.

  • Wickremsinghe, I., R, M. T. B. V., Mot, Y. Y., Dhanoa, A., S, H. S, 2018. Identification of Differentially Expressed Genes in BALB/c Mouse Liver upon Primary Infection with DENV1 and Sequential Heterologous Infection with DENV2, Pathogens, 7, 78.

  • Wiwanitkit, V, 2005. Immune complex: does it have a role in pathogenesis of renal failure in dengue infection?, Ren Fail, 27, 803-804.

  • Wu, T., Hu, E., Xu, S., Chen, M., Guo, P., Dai, Z., Feng, T., Zhou, L., Tang, W., Zhan, L., Fu, X., Liu, S., Bo, X., Yu, G, 2021. clusterProfiler 4.0: A universal enrichment tool for interpreting omics data, Innovation (Camb). 2, 100141.

  • Yang, W., Liu, L. B., Liu, F. L., Wu, Y. H., Zhen, Z. D., Fan, D. Y., Sheng, Z. Y., Song, Z. R., Chang, J. T., Zheng, Y. T., An, J., Wang, P. G, 2023. Single-cell RNA sequencing reveals the fragility of male spermatogenic cells to Zika virus-induced complement activation, Nat Commun, 14, 2476.

  • Yuan, Y., Chen, Q., Li, Z., Cai, F., Li, D., Wang, W, 2025. Single-cell sequencing reveals the features of adaptive immune responses in the liver of a mouse model of dengue fever, Animal Model Exp Med, 8, 30-43.

  • Zeng, Z., Zhan, J., Chen, L., Chen, H., Cheng, S, 2021. Global, regional, and national dengue burden from 1990 to 2017: A systematic analysis based on the global burden of disease study 2017, EClinicalMedicine, 32, 100712.

  • Zheng, W., Wang, X., Liu, J., Yu, X., Li, L., Wang, H., Yu, J., Pei, X., Li, C., Wang, Z., Zhang, M., Zeng, X., Zhang, F., Wang, C., Chen, H., Chen, H. Z, 2022. Single-cell analyses highlight the proinflammatory contribution of C1q-high monocytes to Behcet's disease, Proc Natl Acad Sci U S A, 119, e2204289119.

  • Zheng, X., Chen, H., Wang, R., Fan, D., Feng, K., Gao, N., An, J, 2017. Effective Protection Induced by a Monovalent DNA Vaccine against Dengue Virus (DV) Serotype 1 and a Bivalent DNA Vaccine against DV1 and DV2 in Mice, Front Cell Infect Microbiol, 7, 175.