-
Berning BA, Walker AK, 2019: The pathobiology of TDP-43 C-terminal fragments in ALS and FTLD[J]. Front Neurosci, 13, 335-. doi: 10.3389/fnins.2019.00335
-
Buratti E, Brindisi A, Giombi M, Tisminetzky S, Ayala YM, Baralle FE, 2005: TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing[J]. J Biol Chem, 280, 37572-37584. doi: 10.1074/jbc.M505557200
-
Cai Q, Yameen M, Liu W, Gao Z, Li Y, Peng X, Cai Y, Wu C, Zheng Q, Li J, Lin T, 2013: Conformational plasticity of the 2A proteinase from enterovirus 71[J]. J Virol, 87, 7348-7356. doi: 10.1128/JVI.03541-12
-
Caine EA, Moncla LH, Ronderos MD, Friedrich TC, Osorio JE, 2016: A single mutation in the VP1 of enterovirus 71 is responsible for increased virulence and neurotropism in adult interferon-deficient mice[J]. J Virol, 90, 8592-8604. doi: 10.1128/JVI.01370-16
-
Chang PC, Chen SC, Chen KT, 2016: The current status of the disease caused by enterovirus 71 infections: epidemiology, pathogenesis, molecular epidemiology, and vaccine development[J]. Int J Environ Res Public Health, 13, 890-. doi: 10.3390/ijerph13090890
-
Chen YF, Hu L, Xu F, Liu CJ, Li J, 2019: A case report of a teenager with severe hand, foot, and mouth disease with brainstem encephalitis caused by enterovirus 71[J]. BMC Pediatr, 19, 59-. doi: 10.1186/s12887-019-1428-4
-
Colombrita C, Onesto E, Megiorni F, Pizzuti A, Baralle FE, Buratti E, Silani V, Ratti A, 2012: TDP-43 and FUS RNA-binding proteins bind distinct sets of cytoplasmic messenger rnas and differently regulate their post-transcriptional fate in motoneuron-like cells[J]. J Biol Chem, 287, 15635-15647. doi: 10.1074/jbc.M111.333450
-
Donde A, Sun M, Jeong YH, Wen X, Ling J, Lin S, Braunstein K, Nie S, Wang S, Chen L, Wong PC, 2020: Upregulation of ATG7 attenuates motor neuron dysfunction associated with depletion of TARDBP/TDP-43[J]. Autophagy, 16, 672-682. doi: 10.1080/15548627.2019.1635379
-
Duan H, Zhu M, Xiong Q, Wang Y, Xu C, Sun J, Wang C, Zhang H, Xu P, Peng Y, 2017: Regulation of enterovirus 2A protease-associated viral IRES activities by the cell's ERK signaling cascade: implicating ERK as an efficiently antiviral target[J]. Antiviral Res, 143, 13-21. doi: 10.1016/j.antiviral.2017.03.018
-
Ertel KJ, Brunner JE, Semler BL, 2010: Mechanistic consequences of hnRNP C binding to both RNA termini of poliovirus negative-strand RNA intermediates[J]. J Virol, 84, 4229-4242. doi: 10.1128/JVI.02198-09
-
Feng Q, Langereis MA, Lork M, Nguyen M, Hato SV, Lanke K, Emdad L, Bhoopathi P, Fisher PB, Lloyd RE, van Kuppeveld FJ, 2014: Enterovirus 2Apro targets MDA5 and MAVS in infected cells[J]. J Virol, 88, 3369-3378. doi: 10.1128/JVI.02712-13
-
Feng M, Guo S, Fan S, Zeng X, Zhang Y, Liao Y, Wang J, Zhao T, Wang L, Che Y, Wang J, Ma N, Liu L, Yue L, Li Q, 2016: The preferential infection of astrocytes by enterovirus 71 plays a key role in the viral neurogenic pathogenesis[J]. Front Cell Infect Microbiol, 6, 192-.
-
Fiesel FC, Weber SS, Supper J, Zell A, Kahle PJ, 2012: TDP-43 regulates global translational yield by splicing of exon junction complex component SKAR[J]. Nucleic Acids Res, 40, 2668-2682. doi: 10.1093/nar/gkr1082
-
Freibaum BD, Chitta RK, High AA, Taylor JP, 2010: Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery[J]. J Proteome Res, 9, 1104-1120. doi: 10.1021/pr901076y
-
Fung G, Shi J, Deng H, Hou J, Wang C, Hong A, Zhang J, Jia W, Luo H, 2015: Cytoplasmic translocation, aggregation, and cleavage of TDP-43 by enteroviral proteases modulate viral pathogenesis[J]. Cell Death Differ, 22, 2087-2097. doi: 10.1038/cdd.2015.58
-
Gao J, Wang L, Yan T, Perry G, Wang X, 2019: TDP-43 proteinopathy and mitochondrial abnormalities in neurodegeneration[J]. Mol Cell Neurosci, 100, 103396-. doi: 10.1016/j.mcn.2019.103396
-
Gerhauser I, Hansmann F, Ciurkiewicz M, Loscher W, Beineke A, 2019: Facets of theiler's murine encephalomyelitis virus-induced diseases: an update[J]. Int J Mol Sci, 20, 448-. doi: 10.3390/ijms20020448
-
Guo Z, Zhong X, Lin L, Wu S, Wang T, Chen Y, Zhai X, Wang Y, Wu H, Tong L, Han Y, Pan B, Peng Y, Si X, Zhang F, Zhao W, Zhong Z, 2014: A 3C(pro)-dependent bioluminescence imaging assay for in vivo evaluation of anti-enterovirus 71 agents[J]. Antiviral Res, 101, 82-92. doi: 10.1016/j.antiviral.2013.11.002
-
Hart MP, Gitler AD, 2012: ALS-associated ataxin 2 polyq expansions enhance stress-induced caspase 3 activation and increase TDP-43 pathological modifications[J]. J Neurosci, 32, 9133-9142. doi: 10.1523/JNEUROSCI.0996-12.2012
-
Holmes CW, Koo SS, Osman H, Wilson S, Xerry J, Gallimore CI, Allen DJ, Tang JW, 2016: Predominance of enterovirus B and echovirus 30 as cause of viral meningitis in a UK population[J]. J Clin Virol, 81, 90-93. doi: 10.1016/j.jcv.2016.06.007
-
Huang CC, Liu CC, Chang YC, Chen CY, Wang ST, Yeh TF, 1999: Neurologic complications in children with enterovirus 71 infection[J]. N Engl J Med, 341, 936-942. doi: 10.1056/NEJM199909233411302
-
Huang Q, Wang Y, Si C, Zhao D, Wang Y, Duan Y, 2017: Interleukin-35 modulates the imbalance between regulatory T cells and T helper 17 cells in enterovirus 71-induced hand, foot, and mouth disease[J]. J Interferon Cytokine Res, 37, 522-530. doi: 10.1089/jir.2017.0080
-
Hung HC, Chen TC, Fang MY, Yen KJ, Shih SR, Hsu JT, Tseng CP, 2010: Inhibition of enterovirus 71 replication and the viral 3d polymerase by aurintricarboxylic acid[J]. J Antimicrob Chemother, 65, 676-683. doi: 10.1093/jac/dkp502
-
Ju Y, Tan Z, Huang H, Chen M, Tan Y, Zhang C, Wang J, Wang H, Chen M, 2020: Clinical and epidemiological characteristics of coxsackievirus a6- and enterovirus 71-associated clinical stage 2 and 3 severe hand, foot, and mouth disease in Guangxi, Southern China, 2017[J]. J Infect, 80, 121-142.
-
Lee KY, 2016: Enterovirus 71 infection and neurological complications[J]. Korean J Pediatr, 59, 395-401. doi: 10.3345/kjp.2016.59.10.395
-
Lei X, Liu X, Ma Y, Sun Z, Yang Y, Jin Q, He B, Wang J, 2010: The 3C protein of enterovirus 71 inhibits retinoid acid-inducible gene I-mediated interferon regulatory factor 3 activation and type I interferon responses[J]. J Virol, 84, 8051-8061. doi: 10.1128/JVI.02491-09
-
Lei X, Sun Z, Liu X, Jin Q, He B, Wang J, 2011: Cleavage of the adaptor protein TRIF by enterovirus 71 3C inhibits antiviral responses mediated by toll-like receptor 3[J]. J Virol, 85, 8811-8818. doi: 10.1128/JVI.00447-11
-
Lei X, Zhang Z, Xiao X, Qi J, He B, Wang J, 2017: Enterovirus 71 inhibits pyroptosis through cleavage of gasdermin D[J]. J Virol, 91, e01069-.
-
Levengood JD, Tolbert M, Li ML, Tolbert BS, 2013: High-affinity interaction of hnRNP A1 with conserved RNA structural elements is required for translation and replication of enterovirus 71[J]. RNA Biol, 10, 1136-1145. doi: 10.4161/rna.25107
-
Li B, Yue Y, Zhang Y, Yuan Z, Li P, Song N, Lin W, Liu Y, Gu L, Meng H, 2017: A novel enterovirus 71 (ev71) virulence determinant: the 69th residue of 3C protease modulates pathogenicity[J]. Front Cell Infect Microbiol, 7, 26-.
-
Li J, Gao F, Hao SB, Cheng D, Zhang WQ, Lin B, Zhao L, Yu XJ, Wang ZY, Wen HL, 2017: Contribution of 3CD region to the virulence of enterovirus 71[J]. Biomed Environ Sci, 30, 767-771.
-
Masaki K, Sonobe Y, Ghadge G, Pytel P, Roos RP, 2019: TDP-43 proteinopathy in theiler's murine encephalomyelitis virus infection[J]. PLoS Pathog, 15, e1007574-. doi: 10.1371/journal.ppat.1007574
-
McCluskey LF, Elman LB, Martinez-Lage M, Van Deerlin V, Yuan W, Clay D, Siderowf A, Trojanowski JQ, 2009: Amyotrophic lateral sclerosis-plus syndrome with TAR DNA-binding protein-43 pathology[J]. Arch Neurol, 66, 121-124.
-
Park N, Schweers NJ, Gustin KE, 2015: Selective removal of FG repeat domains from the nuclear pore complex by enterovirus 2A(pro)[J]. J Virol, 89, 11069-11079. doi: 10.1128/JVI.00956-15
-
Riku Y, Watanabe H, Yoshida M, Tatsumi S, Mimuro M, Iwasaki Y, Katsuno M, Iguchi Y, Masuda M, Senda J, Ishigaki S, Udagawa T, Sobue G, 2014: Lower motor neuron involvement in TAR DNA-binding protein of 43 kDa-related frontotemporal lobar degeneration and amyotrophic lateral sclerosis[J]. JAMA Neurol, 71, 172-179. doi: 10.1001/jamaneurol.2013.5489
-
Riku Y, Watanabe H, Yoshida M, Mimuro M, Iwasaki Y, Masuda M, Ishigaki S, Katsuno M, Sobue G, 2016: Marked involvement of the striatal efferent system in TAR DNA-binding protein 43 kDa-related frontotemporal lobar degeneration and amyotrophic lateral sclerosis[J]. J Neuropathol Exp Neurol, 75, 801-811. doi: 10.1093/jnen/nlw053
-
Rohn TT, 2009: Cytoplasmic inclusions of TDP-43 in neurodegenerative diseases: a potential role for caspases[J]. Histol Histopathol, 24, 1081-1086.
-
Romano M, Buratti E, Romano G, Klima R, Del Bel Belluz L, Stuani C, Baralle F, Feiguin F, 2014: Evolutionarily conserved heterogeneous nuclear ribonucleoprotein (hnRNP) A/B proteins functionally interact with human and drosophila TAR DNA-binding protein 43 (TDP-43)[J]. J Biol Chem, 289, 7121-7130. doi: 10.1074/jbc.M114.548859
-
Shimonaka S, Nonaka T, Suzuki G, Hisanaga S, Hasegawa M, 2016: Templated aggregation of TAR DNA-binding protein of 43 kDa (TDP-43) by seeding with TDP-43 peptide fibrils[J]. J Biol Chem, 291, 8896-8907. doi: 10.1074/jbc.M115.713552
-
Sun D, Chen S, Cheng A, Wang M, 2016: Roles of the picornaviral 3C proteinase in the viral life cycle and host cells[J]. Viruses, 8, 82-. doi: 10.3390/v8030082
-
Takahashi S, Liao Q, Van Boeckel TP, Xing W, Sun J, Hsiao VY, Metcalf CJ, Chang Z, Liu F, Zhang J, Wu JT, Cowling BJ, Leung GM, Farrar JJ, van Doorn HR, Grenfell BT, Yu H, 2016: Hand, foot, and mouth disease in china: modeling epidemic dynamics of enterovirus serotypes and implications for vaccination[J]. PLoS Med, 13, e1001958-. doi: 10.1371/journal.pmed.1001958
-
Teoh HL, Mohammad SS, Britton PN, Kandula T, Lorentzos MS, Booy R, Jones CA, Rawlinson W, Ramachandran V, Rodriguez ML, Andrews PI, Dale RC, Farrar MA, Sampaio H, 2016: Clinical characteristics and functional motor outcomes of enterovirus 71 neurological disease in children[J]. JAMA Neurol, 73, 300-307. doi: 10.1001/jamaneurol.2015.4388
-
Tolbert M, Morgan CE, Pollum M, Crespo-Hernandez CE, Li ML, Brewer G, Tolbert BS, 2017: HnRNP A1 alters the structure of a conserved enterovirus IRES domain to stimulate viral translation[J]. J Mol Biol, 429, 2841-2858. doi: 10.1016/j.jmb.2017.06.007
-
Tudor EL, Galtrey CM, Perkinton MS, Lau KF, De Vos KJ, Mitchell JC, Ackerley S, Hortobagyi T, Vamos E, Leigh PN, Klasen C, McLoughlin DM, Shaw CE, Miller CC, 2010: Amyotrophic lateral sclerosis mutant vesicle-associated membrane protein-associated protein-B transgenic mice develop TAR-DNA-binding protein-43 pathology[J]. Neuroscience, 167, 774-785. doi: 10.1016/j.neuroscience.2010.02.035
-
Ule J, 2008: Ribonucleoprotein complexes in neurologic diseases[J]. Curr Opin Neurobiol, 18, 516-523. doi: 10.1016/j.conb.2008.09.018
-
Wang B, Xi X, Lei X, Zhang X, Cui S, Wang J, Jin Q, Zhao Z, 2013: Enterovirus 71 protease 2Apro targets MAVS to inhibit anti-viral type I interferon responses[J]. PLoS Pathog, 9, e1003231-. doi: 10.1371/journal.ppat.1003231
-
Wang C, Sun M, Yuan X, Ji L, Jin Y, Cardona CJ, Xing Z, 2017: Enterovirus 71 suppresses interferon responses by blocking janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling through inducing karyopherin-alpha1 degradation[J]. J Biol Chem, 292, 10262-10274. doi: 10.1074/jbc.M116.745729
-
Wang T, Wang B, Huang H, Zhang C, Zhu Y, Pei B, Cheng C, Sun L, Wang J, Jin Q, Zhao Z, 2017: Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication[J]. PLoS Pathog, 13, e1006674-. doi: 10.1371/journal.ppat.1006674
-
Watters K, Palmenberg AC, 2011: Differential processing of nuclear pore complex proteins by rhinovirus 2A proteases from different species and serotypes[J]. J Virol, 85, 10874-10883. doi: 10.1128/JVI.00718-11
-
Watters K, Inankur B, Gardiner JC, Warrick J, Sherer NM, Yin J, Palmenberg AC, 2017: Differential disruption of nucleocytoplasmic trafficking pathways by rhinovirus 2A proteases[J]. J Virol, 91, e02472-.
-
Wobst HJ, Delsing L, Brandon NJ, Moss SJ, 2017: Truncation of the TAR DNA-binding protein 43 is not a prerequisite for cytoplasmic relocalization, and is suppressed by caspase inhibition and by introduction of the a90v sequence variant[J]. PLoS ONE, 12, e0177181-. doi: 10.1371/journal.pone.0177181
-
Wong J, Si X, Angeles A, Zhang J, Shi J, Fung G, Jagdeo J, Wang T, Zhong Z, Jan E, Luo H, 2013: Cytoplasmic redistribution and cleavage of AUF1 during coxsackievirus infection enhance the stability of its viral genome[J]. FASEB J, 27, 2777-2787. doi: 10.1096/fj.12-226498
-
Wu S, Wang Y, Lin L, Si X, Wang T, Zhong X, Tong L, Luan Y, Chen Y, Li X, Zhang F, Zhao W, Zhong Z, 2014: Protease 2A induces stress granule formation during coxsackievirus b3 and enterovirus 71 infections[J]. Virol J, 11, 192-. doi: 10.1186/s12985-014-0192-1
-
Zhang YJ, Xu YF, Dickey CA, Buratti E, Baralle F, Bailey R, Pickering-Brown S, Dickson D, Petrucelli L, 2007: Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43[J]. J Neurosci, 27, 10530-10534. doi: 10.1523/JNEUROSCI.3421-07.2007
-
Zhao T, Zhang Z, Zhang Y, Feng M, Fan S, Wang L, Liu L, Wang X, Wang Q, Zhang X, Wang J, Liao Y, He Z, Lu S, Yang H, Li Q, 2017: Dynamic interaction of enterovirus 71 and dendritic cells in infected neonatal rhesus macaques[J]. Front Cell Infect Microbiol, 7, 171-. doi: 10.3389/fcimb.2017.00171