Figure 5个  Table 1个
    • Category and band no. Protein score Mass (kDa) Gene name Protein description No. of unique peptides No. of peptides SC (%) Category and band no. Protein score Mass (kDa) Gene name Protein description No. of unique peptides No. of peptides SC (%)
      RHDV protein Cytoskeleton
      6 273.3 57.8 RdRp RHDV RdRp 3 4 21.1 11 105.5 14.3 CFL1 Cofilin 1 2 6 16.8
      10 186.4 25.1 p23 RHDV p23 2 3 15.5 3 316.5 102.9 ACTN1 Actinin alpha 1 2 7 32.4
      11 165.8 16.2 p16 RHDV p16 2 4 10.4 4 286.3 87.4 ACTN4 Actinin alpha 4 2 6 28.5
      Transport 8 357.8 41.7 ACTB Actin, cytoplasmic 1 2 5 19.0
      8 57.1 39.2 ANXA2 Annexin A2 4 7 10.4 7 419.4 53.6 VIM Vimentin 13 13 25.3
      1 201.3 233.6 PI4KA Phosphatidylinositol 4-kinase alpha 6 6 30.5 Chaperon
      5 303.5 68.9 ALB Serum albumin 8 10 15.2 7 65.2 45.1 CSNK2A1 Casein kinase Ⅱ subunit alpha 5 5 7.5
      11 287.6 15.6 HBA hemoglobin subunit alpha 5 5 40.4 4 236.2 71.0 HSPA8 Heat shock cognate 71 kDa protein 7 7 14.2
      6 173.2 59.7 ATP5A1 F-type H+-transporting ATPase subunit beta 3 3 7.8 9 153.9 30.7 PYCR2 Pyrroline-5-carboxylate reductase 4 5 16.8
      11 365.6 16.1 HBB Hemoglobin subunit beta 7 9 58.7 3 70.1 116.8 DSG1 Desmoglein 1 2 5 9.0
      11 365.6 16.1 HBB Hemoglobin subunit beta 7 9 58.7 11 50.3 14.7 LYZ Lysozyme C 2 3 11.5
      9 98.3 32.9 SLC25A5 Solute carrier family 25 3 3 11.2 4 53.5 73.5 HSPA9 Eat shock protein family A (Hsp70) member 9 2 2 13.8
      11 99.8 12.6 FABP5 Fatty acid-binding protein 5 3 4 13.5 10 152.2 26.2 NUDT21 Nudix hydrolase 21 3 3 24.5
      RNP complex 8 142.8 40.3 PDCD2L Programmed cell death protein 2-like 4 4 28.7
      10 78.5 25.7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1 3 7 13. 6 11 108.3 16.0 FAM207A Family with sequence similarity 207 member A 5 8 19.6
      10 67.9 30.3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 2 6 8.9 Translation machines
      7 127.2 50.9 HNRNPK Heterogeneous nuclear ribonucleoprotein K 4 9 11.6 7 94.2 50.0 EEF1A Elongation factor 1-alpha 7 7 9.3
      5 87.0 67.5 DDX5 DEAD-box helicase 5 2 4 8.3 11 135.4 17.7 RPS18 Ribosomal protein S18 4 4 18.7
      5 90.6 69.4 NCL Nucleolin 8 10 28.8 11 113.3 16.3 AAES 40S ribosomal protein S14 3 3 28.3
      2 117.8 130.7 SORBS2 Sorbin and SH3 domain containing 2 5 5 14.7 10 174.3 20.2 RPL11 Ribosomal protein L11 4 4 20.1
      10 135.6 26.2 NUDT21 cleavage and polyadenylation specificity factor subunit 5 3 3 10.4 10 283.1 21.2 RPL12 Ribosomal protein L12 5 5 33.5
      5 99.1 70.9 PABPC1 Polyadenylate-binding protein 1 4 4 16.3 11 164.9 12.8 RPL30 60S ribosomal protein L30 4 4 50.5
      9 128.4 36.0 YBX1 Nuclease sensitive element-binding protein 1 5 6 22.1 11 68.3 15.5 RPS17 40S ribosomal protein S17 3 3 29.6
      6 112.1 57.4 PTBP1 Polypyrimidine tract-binding protein 1 4 7 6.7 10 323.2 22.9 RPS5 Ribosomal protein S5 7 7 18.5
      6 65.2 52.1 SRSF1 Splicing factor, arginine/serine-rich 1 6 7 8.8 9 258.2 31.1 RPS3 40S ribosomal protein S3 9 9 25.8
      5 75.9 63.5 CPSF6 Cleavage and polyadenylation specificity factor subunit 6/7 3 10 10.9 7 74.4 45.3 EIF4A1 Eukaryotic initiation factor 4A-I 4 6 9.7
      6 75.2 62.5 DDX41 Probable ATP-dependent RNA helicase 3 12 14.5 11 122.6 13.7 RPS25 Ribosomal protein S25 5 5 21.3
      11 75.3 14.0 RPS15A Ribosomal protein S15a 2 5 18.3
      a Protein lists for each of the proteins identified in Fig. 2B. SC (%) refers to the percent sequence coverage for the protein.

      Table 1.  Categories of host factors found to be associated with RHDV replicasea.