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pseudovirus clone length of gp160 Amino acid residues corresponding to HXB2 position ID50 of b12
(μg/mL)Group strain 22 182 276 334 346 386 466 474 698 778 786 S1 GX93.1 857 L V N S R N T N I A G > 25 GX93.2 848 * * * * * * N * * * * > 25 GX93.3 857 * * * * * * * * * * * > 25 GX93.4 848 * * * * * * * * * * * > 25 S2 GX93.5 852 * * * * * * * * * * * 5.356 GX93.6 852 * * * * * * * * * * * 2.859 GX93.7 852 * * * * * * * * * * * 2.255 S3 GX93.8 848 * * * * * * * * * * * 0.734 GX93.9 852 * * * * * * * * * * * 0.454 GX93.10 857 * * * * * * * * * * * 0.325 GX93.11 852 * * * * * * * * * * * 0.280 GX93.12 852 * * * * * * * * * * * 0.258 GX93.13 852 * * * * * * * * * * * 0.230 GX93.14 852 * * * * * * * * * * * 0.188 GX93.15 852 * * * * * * * * * * * 0.172 GX93.16 852 * * * * * * * * * * * 0.167 GX93.17 852 * * * * * * G * V T R 0.117 S4 GX93.18 848 F L S N S D G D V T R 0.092 GX93.19 848 F L D N S D G D V T R 0.080 GX93.20 848 F L S N S D G D V T R 0.040 GX93.21 848 F L S N S D G D V T R 0.020 GX93.22 848 F L S N S D G D V T R 0.015 GX93.23 848 F L D N S D G D V T R 0.015 GX93.24 848 F L S N S D G D V T R 0.014 *Amino acids which were identical to the GX93.1 in the same position are designated with a dot. Table 1. Length of gp160 and amino acid substitutions in Env-pseudotyped virus coinciding with variety of sensitivity to b12 neutralization.
Figure 2 个
Table 1 个
