Figure 6个  Table 1
    • Gene name Protein name Fold change LFQ intensity E199L-IP LFQ intensity E199L-IgG Functional description References
      ARL8B ADP-ribosylation factor-like protein 8B 3.428346353 44, 963, 000 0 A critical regulator of cargo delivery to lysosomes (Garg et al. 2011)
      LAMP2 lysosomal associated membrane protein 2 3.365582298 36, 729, 000 0 An important role in autophagosome formation (Fukushima et al. 2020) (Nguyen et al. 2018)
      PYCR2 Pyrroline-5-carboxylate reductase 2 58.15290957 351, 840, 000 0 Downregulation of PYCR2 induces the autophagy (Ou et al. 2016)
      BAG5 BAG family molecular chaperone regulator 5 32.82806482 101, 330, 000 0 Bcl-2-associated BAG5 regulates autophagy (De snoo et al. 2019)
      FLII Protein flightless 1 homolog 3.152638472 16, 234, 000 0 FLII interacts with p62 to block its recognition of LC3 (He et al. 2018)

      Table 1.  Potential E199L-interacting proteins which are related to cell autophagy.