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Gene name Protein name Fold change LFQ intensity E199L-IP LFQ intensity E199L-IgG Functional description References ARL8B ADP-ribosylation factor-like protein 8B 3.428346353 44, 963, 000 0 A critical regulator of cargo delivery to lysosomes (Garg et al. 2011) LAMP2 lysosomal associated membrane protein 2 3.365582298 36, 729, 000 0 An important role in autophagosome formation (Fukushima et al. 2020) (Nguyen et al. 2018) PYCR2 Pyrroline-5-carboxylate reductase 2 58.15290957 351, 840, 000 0 Downregulation of PYCR2 induces the autophagy (Ou et al. 2016) BAG5 BAG family molecular chaperone regulator 5 32.82806482 101, 330, 000 0 Bcl-2-associated BAG5 regulates autophagy (De snoo et al. 2019) FLII Protein flightless 1 homolog 3.152638472 16, 234, 000 0 FLII interacts with p62 to block its recognition of LC3 (He et al. 2018) Table 1. Potential E199L-interacting proteins which are related to cell autophagy.
Figure 6 个
Table 1 个