Figure 2个  Table 1
    • Proteins Substitutionsa Functions SZ-SMGC-1 Pakistan-06 Other strains from China
      Amino acids No. (%)
      nsp1 T128K NA K K K 21 (95.5)
      T 1 (4.5)
      nsp2 S54N NA N N N 21 (95.5)
      S 1(4.5)
      H374Y NA Y Y Y 21 (95.5)
      H 1 (4.5)
      L539S NA L L L 12 (54.5)
      S 10(46.5)
      nsp3 524 NA Stop codon R Stop codon 20 (909)
      R 2 (9.1)
      nsp4 L43A NA A A A 22 (100)
      L 0 0)
      R82S NA R R R 12 (54.5)
      S 10(46.5)
      T254A NA A A A 21(95.5)
      T 1(4.5)
      A 366T NA T T T 21(95.5)
      A 1(4.5)
      Q500L NA L L L 22 (100)
      Q 0 (0)
      E2 A164T NA T T T 22 (100)
      A 0(0)
      I211T Potentiate the ECSA genotype for the finess-increasing effect of A226V T T T 21 (95.5)
      I 1 (4.5)
      K252Q Enhance the infection eficiency to A. albopictus K K K 10 (46.5)
      Q 12 (54.5)
      V386A NA A A A 21 (95.5)
      V 1 (4.5)
      E1 S72N NA N N N 22 (100)
      S 0(0)
      E211K NA E E E 7 (31.8)
      K 15 (68.2)
      A226V Increased fitness to the A. albopictus A A A 10 (46.5)
      V 12 (54.5)
      D284E Influence the icosahedral E1-scaffold and increase transmissibility E E E 21 (95.5)
      D 1 (4.5)
      NA not available, ECSA East Central
      aSouth African."Specific substitutions for viruses from ECSA lineage were shown.

      Table 1.  Key amino acid substitutions of the SZ-SMGC-1 and the other isolates in China.